Complex Systems and Computational Biology Approaches to Acute Inflammation

Complex Systems and Computational Biology Approaches to Acute Inflammation

A Framework for Model-based Precision Medicine

An, Gary; Vodovotz, Yoram

Springer Nature Switzerland AG

11/2021

312

Mole

Inglês

9783030565121

15 a 20 dias

498

Descrição não disponível.
Part I: OverviewChapter 1: "An Overview of the Translational Dilemma and the Need for Model-based Precision Medicine" Yoram Vodovotz and Gary An
Part II: "Computational Modeling Methods and Biomedical Applications"Chapter 2: Translational Equation-based Modeling -Gilles ClermontChapter 3: Agent-based Modeling in Translational Systems Biology -Gary An Chapter 4: Integrating Data-driven and Mechanistic Modeling in Sepsis and Trauma -Yoram VodovotzChapter 5: Therapeutics as Control:Model-based approaches for control discovery -Chase Cockrell, Judy Day, Gary An
Part III: Translational Modeling of Sepsis and TraumaChapter 6: Disorder of Systemic Inflammation in Sepsis and Trauma: A Systems Perspective -Tim Billiar Chapter 7: Multiscale Equation-based Models: Insights for Inflammation and Physiological Variability -Ioannis AndroulakisChapter 8: In silicoTrials and Personalized Therapy for Sepsis and Trauma -Vodovotz, Bartels and AnChapter 9: Computational Modeling of the Coagulation Response -Scott Diamond
Part IV: Translational Modeling of Organ/Tissue Specific Inflammatory Disease Processes Chapter 10: Disorder of Localized Inflammation in Wound Healing -Stephen BadylakChapter11: Equation-based Models of Wound Healing and Collective Cell Migration -Julia Arciero and David SwigonChapter 12: Agent-based Models of Wound Healing -Yoram Vodovotz and Gary AnChapter 13: Tissue realistic translational modeling of gut inflammation -Chase Cockrell and Gary AnChapter 14: Data-DrivenModeling of Liver Injury, Inflammation, and Fibrosis -Ruben Zamora and Yoram VodovotzChapter 15: Computational Modeling of Tuberculosis -Denise Kirschner
Part V: Future Perspectives: Translation to ImplementationChapter 16: "The Rationale and Implementation of Model-based Precision Medicine for Inflammatory Diseases"Gary An and Yoram Vodovotz
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inflammation;modeling;systems biology;critical illness;computational modeling;trauma