Mammalian Heme Peroxidases
portes grátis
Mammalian Heme Peroxidases
Diverse Roles in Health and Disease
Hawkins, Clare; Nauseef, William M
Taylor & Francis Ltd
10/2021
328
Dura
Inglês
9780367820367
15 a 20 dias
857
Descrição não disponível.
SECTION 1: INTRODUCTION TO MAMMALIAN HEME PEROXIDASES
Structure, function, phylogeny of heme peroxidases
Biosynthesis of MPO and other heme peroxidases
Peroxidasin structure and function
SECTION 2: REACTIVITY OF PEROXIDASE OXIDANTS
Reactivity of peroxidase oxidants with proteins and proteoglycans
Reactivity of peroxidase with nucleic acids, RNA and DNA
Reactivity of peroxidase oxidants with lipids - modification and signaling
Role of MPO in the modification of lipoproteins (LDL and HDL)
Regulation of cellular signaling and survival by peroxidase oxidants
Global profiling of cell responses to peroxidase oxidants
SECTION 3: PEROXIDASES IN INNATE IMMUNITY
MPO and immune cell recruitment and activation
Role of MPO in extracellular trap release by neutrophils
Imaging HOCl production by neutrophils
How microbes combat reactive chlorine species
Priming the innate immune system to combat respiratory disease
SECTION 4: PEROXIDASES IN PATHOLOGY
Imaging the reactivity of MPO in vivo
Role of MPO in vascular dysfunction and signaling
MPO in ischemic heart disease
Role of MPO in neurodegenerative disease
Role of MPO in kidney disease
Role of peroxidases in respiratory disease
Role of peroxidasins in disease
SECTION 5: PREVENTION OF MPO INDUCED DAMAGE
Design and functionality of MPO inhibitors
Modulation of disease using MPO inhibitors
Novel peroxidase inhibitory protein "SPIN" with broad target specificity
Selenium and resistance to oxidative enzyme inactivation
Structure, function, phylogeny of heme peroxidases
Biosynthesis of MPO and other heme peroxidases
Peroxidasin structure and function
SECTION 2: REACTIVITY OF PEROXIDASE OXIDANTS
Reactivity of peroxidase oxidants with proteins and proteoglycans
Reactivity of peroxidase with nucleic acids, RNA and DNA
Reactivity of peroxidase oxidants with lipids - modification and signaling
Role of MPO in the modification of lipoproteins (LDL and HDL)
Regulation of cellular signaling and survival by peroxidase oxidants
Global profiling of cell responses to peroxidase oxidants
SECTION 3: PEROXIDASES IN INNATE IMMUNITY
MPO and immune cell recruitment and activation
Role of MPO in extracellular trap release by neutrophils
Imaging HOCl production by neutrophils
How microbes combat reactive chlorine species
Priming the innate immune system to combat respiratory disease
SECTION 4: PEROXIDASES IN PATHOLOGY
Imaging the reactivity of MPO in vivo
Role of MPO in vascular dysfunction and signaling
MPO in ischemic heart disease
Role of MPO in neurodegenerative disease
Role of MPO in kidney disease
Role of peroxidases in respiratory disease
Role of peroxidasins in disease
SECTION 5: PREVENTION OF MPO INDUCED DAMAGE
Design and functionality of MPO inhibitors
Modulation of disease using MPO inhibitors
Novel peroxidase inhibitory protein "SPIN" with broad target specificity
Selenium and resistance to oxidative enzyme inactivation
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Hypohalous Acids;MPO Inhibition;Heme Proteins;Hypothiocyanous Acid;Peroxidase Oxidants;Net;Evolution;MPO Deficient Mouse;Innate Immunity;Anti-neutrophil Cytoplasmic Autoantibodies;Atherosclerosis;Collagen Iv;Neurodegenerative Disease;Collagen Iv Network;MPO Activity;Net Formation;MPO Expression;EPO;Heme Peroxidases;Human MPO;MPO Gene;Endothelial Dysfunction;NADPH Oxidase;NOX Protein;MPO Deficiency;PECAM-1;Human Coronary Artery Smooth Muscle;Lethal Concentrations;MPO Positive Cell;Compound Ii;Anterior Segment Dysgenesis
SECTION 1: INTRODUCTION TO MAMMALIAN HEME PEROXIDASES
Structure, function, phylogeny of heme peroxidases
Biosynthesis of MPO and other heme peroxidases
Peroxidasin structure and function
SECTION 2: REACTIVITY OF PEROXIDASE OXIDANTS
Reactivity of peroxidase oxidants with proteins and proteoglycans
Reactivity of peroxidase with nucleic acids, RNA and DNA
Reactivity of peroxidase oxidants with lipids - modification and signaling
Role of MPO in the modification of lipoproteins (LDL and HDL)
Regulation of cellular signaling and survival by peroxidase oxidants
Global profiling of cell responses to peroxidase oxidants
SECTION 3: PEROXIDASES IN INNATE IMMUNITY
MPO and immune cell recruitment and activation
Role of MPO in extracellular trap release by neutrophils
Imaging HOCl production by neutrophils
How microbes combat reactive chlorine species
Priming the innate immune system to combat respiratory disease
SECTION 4: PEROXIDASES IN PATHOLOGY
Imaging the reactivity of MPO in vivo
Role of MPO in vascular dysfunction and signaling
MPO in ischemic heart disease
Role of MPO in neurodegenerative disease
Role of MPO in kidney disease
Role of peroxidases in respiratory disease
Role of peroxidasins in disease
SECTION 5: PREVENTION OF MPO INDUCED DAMAGE
Design and functionality of MPO inhibitors
Modulation of disease using MPO inhibitors
Novel peroxidase inhibitory protein "SPIN" with broad target specificity
Selenium and resistance to oxidative enzyme inactivation
Structure, function, phylogeny of heme peroxidases
Biosynthesis of MPO and other heme peroxidases
Peroxidasin structure and function
SECTION 2: REACTIVITY OF PEROXIDASE OXIDANTS
Reactivity of peroxidase oxidants with proteins and proteoglycans
Reactivity of peroxidase with nucleic acids, RNA and DNA
Reactivity of peroxidase oxidants with lipids - modification and signaling
Role of MPO in the modification of lipoproteins (LDL and HDL)
Regulation of cellular signaling and survival by peroxidase oxidants
Global profiling of cell responses to peroxidase oxidants
SECTION 3: PEROXIDASES IN INNATE IMMUNITY
MPO and immune cell recruitment and activation
Role of MPO in extracellular trap release by neutrophils
Imaging HOCl production by neutrophils
How microbes combat reactive chlorine species
Priming the innate immune system to combat respiratory disease
SECTION 4: PEROXIDASES IN PATHOLOGY
Imaging the reactivity of MPO in vivo
Role of MPO in vascular dysfunction and signaling
MPO in ischemic heart disease
Role of MPO in neurodegenerative disease
Role of MPO in kidney disease
Role of peroxidases in respiratory disease
Role of peroxidasins in disease
SECTION 5: PREVENTION OF MPO INDUCED DAMAGE
Design and functionality of MPO inhibitors
Modulation of disease using MPO inhibitors
Novel peroxidase inhibitory protein "SPIN" with broad target specificity
Selenium and resistance to oxidative enzyme inactivation
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Hypohalous Acids;MPO Inhibition;Heme Proteins;Hypothiocyanous Acid;Peroxidase Oxidants;Net;Evolution;MPO Deficient Mouse;Innate Immunity;Anti-neutrophil Cytoplasmic Autoantibodies;Atherosclerosis;Collagen Iv;Neurodegenerative Disease;Collagen Iv Network;MPO Activity;Net Formation;MPO Expression;EPO;Heme Peroxidases;Human MPO;MPO Gene;Endothelial Dysfunction;NADPH Oxidase;NOX Protein;MPO Deficiency;PECAM-1;Human Coronary Artery Smooth Muscle;Lethal Concentrations;MPO Positive Cell;Compound Ii;Anterior Segment Dysgenesis
