Pluripotent Stem Cell Therapy for Diabetes
portes grátis
Pluripotent Stem Cell Therapy for Diabetes
Kieffer, Timothy J .; Sordi, Valeria; Piemonti, Lorenzo; de Koning, Eelco; Odorico, Jon
Springer International Publishing AG
02/2024
602
Dura
Inglês
9783031419423
15 a 20 dias
Descrição não disponível.
Mimicking pancreas development with human pluripotent stem cells.- Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming.- The evolution of methods for in vitro differentiation of stem cell derived islets.- Signaling pathways that govern the formation, expansion and maturation of pancreatic progenitors.- Building islets from the ground up using stem cells.- Pancreatic progenitor proliferation.- Selecting biocompatible biomaterials for stem cell derived islet transplantation.- Scaffolds for encapsulation of stem-cell-derived ? cells.- 3d printing of new islets.- Biological scaffolds and hydrogels in islet organoids.- 3-D organoids of mesenchymal stromal and pancreatic islet cells.- Bioengineered insulin producing endocrine tissues.- Bioactive materials for cell encapsulation.- Strategies to boost islet graft oxygenation.- Vascularizing device strategies.- Immunogenicity of stem cell derived islets.- Immune evasive stemcell islets.- Encapsulation of stem cell-derived islets: recent progress.- Islet immunoengineering.- Stem cell genome editing tools.- Selection of SC-derived pancreatic progenitors and ? cell.- Considerations pertaining to implant sites for cell-based insulin replacement.- Safety switches in pluripotent stem cells.- Safety: teratoma risk.- Stem cell derived islets transplantation in non-human primates.- Social / Legal / Ethical issues pertaining to use of pluripotent stem cells.- Cost-effectiveness considerations for stem cell derived islet replacement therapy.- Lessons from clinical trials of islet cell replacement.- Scale up and Biomanufacturing of Stem Cell- derived Islets.- Minimal SC-? cell properties for transplantation in diabetic patients.- Autologous stem cell islets for patients with chronic pancreatitis and diabetes.- Clinical Trials.- Modeling monogenic diabetes with stem cells.- Stem and progenitor cells in pancreas development, regeneration and drug screening.
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Stem cell;Regenerative medicine;diabetes;autoimmunity;immunoescape;pluripotent stem cells;tissue engineering diabetes;stem cell diabetes;regenerative medicine diabetes;autoimmunity diabetes;pluripotent stem cells diabetes
Mimicking pancreas development with human pluripotent stem cells.- Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming.- The evolution of methods for in vitro differentiation of stem cell derived islets.- Signaling pathways that govern the formation, expansion and maturation of pancreatic progenitors.- Building islets from the ground up using stem cells.- Pancreatic progenitor proliferation.- Selecting biocompatible biomaterials for stem cell derived islet transplantation.- Scaffolds for encapsulation of stem-cell-derived ? cells.- 3d printing of new islets.- Biological scaffolds and hydrogels in islet organoids.- 3-D organoids of mesenchymal stromal and pancreatic islet cells.- Bioengineered insulin producing endocrine tissues.- Bioactive materials for cell encapsulation.- Strategies to boost islet graft oxygenation.- Vascularizing device strategies.- Immunogenicity of stem cell derived islets.- Immune evasive stemcell islets.- Encapsulation of stem cell-derived islets: recent progress.- Islet immunoengineering.- Stem cell genome editing tools.- Selection of SC-derived pancreatic progenitors and ? cell.- Considerations pertaining to implant sites for cell-based insulin replacement.- Safety switches in pluripotent stem cells.- Safety: teratoma risk.- Stem cell derived islets transplantation in non-human primates.- Social / Legal / Ethical issues pertaining to use of pluripotent stem cells.- Cost-effectiveness considerations for stem cell derived islet replacement therapy.- Lessons from clinical trials of islet cell replacement.- Scale up and Biomanufacturing of Stem Cell- derived Islets.- Minimal SC-? cell properties for transplantation in diabetic patients.- Autologous stem cell islets for patients with chronic pancreatitis and diabetes.- Clinical Trials.- Modeling monogenic diabetes with stem cells.- Stem and progenitor cells in pancreas development, regeneration and drug screening.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
