Molecular Basis of Developmental and Stem Cell Regulation

Part I. Somatic Cell Development from the Epiblast.- Chapter 1. The Epiblast and Pluripotent Stem Cell Lines.- Chapter 2. Different Types of Pluripotent Stem Cells Represent Different Developmental Stages.- Chapter 3. Gastrulation: Its Principles and Variations.- Chapter 4. How the Brain Develops from the Epiblast: The Node Is Not an Organizer.- Part II.- New Conceptions of Developmental Regulations.- Chapter 5. Multiple Cell Lineages Give Rise to a Cell Type.- Chapter 6. Organ Regeneration without Relying on Regeneration-Dedicated Stem Cells.- Chapter 7. Reciprocal Interactions Between the Epithelium and Mesenchyme in Oorganogenesis.-Chapter 8. The Significance of Repressive Processes in Developmental Regulation.- Part III. Transcriptional Regulation of Development.- Chapter 9. Enhancer Arrays Regulating Developmental Genes: Sox2 Enhancers as a Paradigm.- Chapter 10. Enhancer Activation by Transcription Factors and Underlying Mechanisms.- Chapter 11. Molecular Basis of Cell Reprogramming into iPSCs with Exogenous Transcription Factors.

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• Biologia do desenvolvimento
• Genética (não médica)
• Biologia Celular (citologia)

Cell Lineage;Cell-Cell Interaction Mechanisms;Developmental Biology;Embryogenesis;Neural Induction Models;Regeneration;Reprogramming;Stem Cells;Stem Cell Biology;Transdifferentiation