Gene and Cellular Immunotherapy for Cancer

Gene and Cellular Immunotherapy for Cancer

Ghobadi, Armin; DiPersio, John F.

Springer Nature Switzerland AG

12/2021

378

Dura

Inglês

9783030878481

15 a 20 dias

746

Descrição não disponível.
The History of Cellular Therapies.- Basics of Immunity.- Biology of CAR T cells.- Cell types used for CAR generation.- Combination therapeutics with CART cell therapy.- Safety switches used for cellular therapies.- Off-the-shelf CAR-T.- Manufacturing of CAR-T Cells: the Assembly Line.- Navigating Regulations in Gene and Cell Immunotherapy .- Bringing CAR-T to the Clinic.- CAR T-Cell Complications.- Mechanisms of Resistance and Relapse after CAR T cell therapy.- Tumor infiltrating lymphocytes (TIL): from bench to bedside.- T-cell Receptor (TCR) Engineered Cells and Their Transition to Clinic.- Viral Cytotoxic T Lymphocytes (CTLs): from Bench to Bedside.- Biology of NK cells and NK cells in clinic.- Biology and Clinical Evaluation of T/NK Cell Engagers.- Roadmap for Starting an Outpatient Cellular Therapy Program.- Index.
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gene immunotherapy;cellular immunotherapy;lymphoma;ALL;CAR-T;NK Cells;T/NK cell engagers;BiTE;DART;TanAbs