Cut-and-Paste Genetics
Cut-and-Paste Genetics
A CRISPR Revolution
Sarkar, Sahotra
Bloomsbury Publishing PLC
09/2021
224
Dura
Inglês
9781786614377
15 a 20 dias
449
Descrição não disponível.
Preface
1.Breeding a Perfect Society
Beginnings: Davenport and eugenics in the United States * IQ and involuntary sterilization * Genetics against eugenics * Exporting sterilization * The Watson scandal * Davenport's dreams today
2.Molecular Diseases, Elusive Treatments
The molecularization of biology * Molecular diseases * But no molecular medicine
*Dreams of editing genes * Followed by stunning failure * Recombinant DNA made no difference * Gene editing BC
3.What Good Was the Human Genome Project?
The sequence revealed * Common diseases and common variants * Medical irrelevance of the sequence * Critiques of the HGP, past and present * Evolution and architecture of the genome * Evolutionary contingency
4.The CRISPR Revolution
The CRISPR structure emerges * Its function is decoded * The mechanism of immunity * Onward to gene editing * The delivery problem * Ubiquitous CRISPR
5.Inevitable Eugenics?
Eugenics in the news * What is eugenics? * Defining eugenics * A working definition * Inescapable eugenics? * Matters of ethics
6.Eliminating Genetic Diseases
The long reach of Huntington's disease * The He Jiankui affair * The ethics of human germ-line intervention * The limits of current science * Gene specificity and Lenin's brain * A policy proposal * Proceed with caution * Liberal and moderate eugenics
7.Designer Baby Delusions
Why not genetic enhancement? * The normal and the enhanced * Liberal eugen- ics and genetic enhancement * Rationality of genetic enhancement * Planned human obsolescence * Where is the science? The case of intelligence * Genomics and IQ * What about physical traits * Genetic reductionism * Contextual developmental construction * What is perfection?
8.A CRISPR Future
Editing the human germ-line * Gene drives * The ethics of promoting extinction
*Biosecurity * CRISPR without the hype
1.Breeding a Perfect Society
Beginnings: Davenport and eugenics in the United States * IQ and involuntary sterilization * Genetics against eugenics * Exporting sterilization * The Watson scandal * Davenport's dreams today
2.Molecular Diseases, Elusive Treatments
The molecularization of biology * Molecular diseases * But no molecular medicine
*Dreams of editing genes * Followed by stunning failure * Recombinant DNA made no difference * Gene editing BC
3.What Good Was the Human Genome Project?
The sequence revealed * Common diseases and common variants * Medical irrelevance of the sequence * Critiques of the HGP, past and present * Evolution and architecture of the genome * Evolutionary contingency
4.The CRISPR Revolution
The CRISPR structure emerges * Its function is decoded * The mechanism of immunity * Onward to gene editing * The delivery problem * Ubiquitous CRISPR
5.Inevitable Eugenics?
Eugenics in the news * What is eugenics? * Defining eugenics * A working definition * Inescapable eugenics? * Matters of ethics
6.Eliminating Genetic Diseases
The long reach of Huntington's disease * The He Jiankui affair * The ethics of human germ-line intervention * The limits of current science * Gene specificity and Lenin's brain * A policy proposal * Proceed with caution * Liberal and moderate eugenics
7.Designer Baby Delusions
Why not genetic enhancement? * The normal and the enhanced * Liberal eugen- ics and genetic enhancement * Rationality of genetic enhancement * Planned human obsolescence * Where is the science? The case of intelligence * Genomics and IQ * What about physical traits * Genetic reductionism * Contextual developmental construction * What is perfection?
8.A CRISPR Future
Editing the human germ-line * Gene drives * The ethics of promoting extinction
*Biosecurity * CRISPR without the hype
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
bioethics; biology; biotechnology; CRISPR; designer babies; Disability; eugenics; gene-editing; genetic disease; genetic enhancement; genetics; genome editing; history of science; Human Genome Project; medical ethics; philosophy of biology; philosophy of science; Race; sterilization
Preface
1.Breeding a Perfect Society
Beginnings: Davenport and eugenics in the United States * IQ and involuntary sterilization * Genetics against eugenics * Exporting sterilization * The Watson scandal * Davenport's dreams today
2.Molecular Diseases, Elusive Treatments
The molecularization of biology * Molecular diseases * But no molecular medicine
*Dreams of editing genes * Followed by stunning failure * Recombinant DNA made no difference * Gene editing BC
3.What Good Was the Human Genome Project?
The sequence revealed * Common diseases and common variants * Medical irrelevance of the sequence * Critiques of the HGP, past and present * Evolution and architecture of the genome * Evolutionary contingency
4.The CRISPR Revolution
The CRISPR structure emerges * Its function is decoded * The mechanism of immunity * Onward to gene editing * The delivery problem * Ubiquitous CRISPR
5.Inevitable Eugenics?
Eugenics in the news * What is eugenics? * Defining eugenics * A working definition * Inescapable eugenics? * Matters of ethics
6.Eliminating Genetic Diseases
The long reach of Huntington's disease * The He Jiankui affair * The ethics of human germ-line intervention * The limits of current science * Gene specificity and Lenin's brain * A policy proposal * Proceed with caution * Liberal and moderate eugenics
7.Designer Baby Delusions
Why not genetic enhancement? * The normal and the enhanced * Liberal eugen- ics and genetic enhancement * Rationality of genetic enhancement * Planned human obsolescence * Where is the science? The case of intelligence * Genomics and IQ * What about physical traits * Genetic reductionism * Contextual developmental construction * What is perfection?
8.A CRISPR Future
Editing the human germ-line * Gene drives * The ethics of promoting extinction
*Biosecurity * CRISPR without the hype
1.Breeding a Perfect Society
Beginnings: Davenport and eugenics in the United States * IQ and involuntary sterilization * Genetics against eugenics * Exporting sterilization * The Watson scandal * Davenport's dreams today
2.Molecular Diseases, Elusive Treatments
The molecularization of biology * Molecular diseases * But no molecular medicine
*Dreams of editing genes * Followed by stunning failure * Recombinant DNA made no difference * Gene editing BC
3.What Good Was the Human Genome Project?
The sequence revealed * Common diseases and common variants * Medical irrelevance of the sequence * Critiques of the HGP, past and present * Evolution and architecture of the genome * Evolutionary contingency
4.The CRISPR Revolution
The CRISPR structure emerges * Its function is decoded * The mechanism of immunity * Onward to gene editing * The delivery problem * Ubiquitous CRISPR
5.Inevitable Eugenics?
Eugenics in the news * What is eugenics? * Defining eugenics * A working definition * Inescapable eugenics? * Matters of ethics
6.Eliminating Genetic Diseases
The long reach of Huntington's disease * The He Jiankui affair * The ethics of human germ-line intervention * The limits of current science * Gene specificity and Lenin's brain * A policy proposal * Proceed with caution * Liberal and moderate eugenics
7.Designer Baby Delusions
Why not genetic enhancement? * The normal and the enhanced * Liberal eugen- ics and genetic enhancement * Rationality of genetic enhancement * Planned human obsolescence * Where is the science? The case of intelligence * Genomics and IQ * What about physical traits * Genetic reductionism * Contextual developmental construction * What is perfection?
8.A CRISPR Future
Editing the human germ-line * Gene drives * The ethics of promoting extinction
*Biosecurity * CRISPR without the hype
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.