Cholesterol and PI(4,5)P2 in Vital Biological Functions
portes grátis
Cholesterol and PI(4,5)P2 in Vital Biological Functions
From Coexistence to Crosstalk
Dantsker, Avia Rosenhouse-
Springer International Publishing AG
03/2023
441
Dura
Inglês
9783031215469
15 a 20 dias
Descrição não disponível.
Preface.- 1. Mutual influence of cholesterol and PI(4,5)P2 on their levels.- Chapter 1. Mechanism of the regulation of plasma cholesterol levels by PI(4,5)P2.- Chapter 2. Effect of cholesterol depletion on ciliary PI(4,5)P2 levels.- Chapter 3. Impact of cholesterol on PI(4,5)P2 levels in the brain.- Chapter 4. Alterations in PIP2 levels in the intracellular cholesterol trafficking disorder NPC1.- Chapter 5. Targeting cholesterol release and PI(4,5)P2 redistribution by the oral drug Miltefosine.- 2. Cross-talk between cholesterol and PI(4,5)P2 as a factor affecting protein function.- A. Plasma membrane ion channels.- Chapter 6. From cross-talk to synergism: the combined effect of cholesterol and PI(4,5)P2 on inwardly rectifying potassium channels.- Chapter 7. Link between lysosomal cholesterol and PI(4,5)P2 in the regulation of the voltage gated KCNQ2/3 potassium channel.- Chapter 8. Cholesterol and PI(4,5)P2 binding to a ciliary membrane transient receptor potential channel.- Chapter 9. Regulation of ell by cholesterol and PI(4,5)P2.- Chapter 10. Cholesterol stimulates the epithelial sodium channel in a PI(4,5)P2-dependent manner.- Chapter 11. Roles of cholesterol and PI(4,5)P2 in store operated calcium entry.- Chapter 12. Roles of cholesterol and PI(4,5)P2 levels in the modulation of the calcium activated chloride channel TMEM16A.- B. Lipid transport proteins--Chapter 13. PI(4,5)P2 facilitates ORP1-mediated cholesterol transport by promoting membrane targeting and cholesterol extraction.- Chapter 14. Role of PI(4,5)P2 binding in ORP2-mediated cholesterol distribution.- Chapter 15. PI(4,5)P2-dependent transport of cholesterol from lysosomes to peroxisomes at lysosomeperoxisome contact sites.- 3. Cellular processes at the intersection of cholesterol and PI(4,5)P2 involvement.- Chapter 16. The insertion of the N-terminal domain of Gasdermin-D is increased byPI(4,5)P2 and decreased by cholesterol.- Chapter 17. Cholesterol promotes the cooperative interaction of formins with PI(4,5)P2 to initiate actin nucleation.- Chapter 18. Cooperation between cholesterol and PI(4,5)P2 in the regulation of Engrailed-2 homeoprotein intercellular trafficking.- Chapter 19. Cholesterol and PI(4,5)P2 as a membrane nanoplatform for HIV assembly.- Chapter 20. Role of Cholesterol and PI(4,5)P2 in the localization of the HIV-1 structural polyprotein Gag to the plasma membrane.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
lipid transfer proteins;cholesterol depletion;PI(4,5)P2;protein function;human disorders;plasma membrane;potassium channels;lyosomal cholesterol;ciliary membrane;thermoTRPs;epithelial sodium channel;lipid transport proteins;cholesterol extraction;lysosomes;peroxisomes;N-terminal;Actin nucleation;Intercellular trafficking;HIV assembly;HIV-1
Preface.- 1. Mutual influence of cholesterol and PI(4,5)P2 on their levels.- Chapter 1. Mechanism of the regulation of plasma cholesterol levels by PI(4,5)P2.- Chapter 2. Effect of cholesterol depletion on ciliary PI(4,5)P2 levels.- Chapter 3. Impact of cholesterol on PI(4,5)P2 levels in the brain.- Chapter 4. Alterations in PIP2 levels in the intracellular cholesterol trafficking disorder NPC1.- Chapter 5. Targeting cholesterol release and PI(4,5)P2 redistribution by the oral drug Miltefosine.- 2. Cross-talk between cholesterol and PI(4,5)P2 as a factor affecting protein function.- A. Plasma membrane ion channels.- Chapter 6. From cross-talk to synergism: the combined effect of cholesterol and PI(4,5)P2 on inwardly rectifying potassium channels.- Chapter 7. Link between lysosomal cholesterol and PI(4,5)P2 in the regulation of the voltage gated KCNQ2/3 potassium channel.- Chapter 8. Cholesterol and PI(4,5)P2 binding to a ciliary membrane transient receptor potential channel.- Chapter 9. Regulation of ell by cholesterol and PI(4,5)P2.- Chapter 10. Cholesterol stimulates the epithelial sodium channel in a PI(4,5)P2-dependent manner.- Chapter 11. Roles of cholesterol and PI(4,5)P2 in store operated calcium entry.- Chapter 12. Roles of cholesterol and PI(4,5)P2 levels in the modulation of the calcium activated chloride channel TMEM16A.- B. Lipid transport proteins--Chapter 13. PI(4,5)P2 facilitates ORP1-mediated cholesterol transport by promoting membrane targeting and cholesterol extraction.- Chapter 14. Role of PI(4,5)P2 binding in ORP2-mediated cholesterol distribution.- Chapter 15. PI(4,5)P2-dependent transport of cholesterol from lysosomes to peroxisomes at lysosomeperoxisome contact sites.- 3. Cellular processes at the intersection of cholesterol and PI(4,5)P2 involvement.- Chapter 16. The insertion of the N-terminal domain of Gasdermin-D is increased byPI(4,5)P2 and decreased by cholesterol.- Chapter 17. Cholesterol promotes the cooperative interaction of formins with PI(4,5)P2 to initiate actin nucleation.- Chapter 18. Cooperation between cholesterol and PI(4,5)P2 in the regulation of Engrailed-2 homeoprotein intercellular trafficking.- Chapter 19. Cholesterol and PI(4,5)P2 as a membrane nanoplatform for HIV assembly.- Chapter 20. Role of Cholesterol and PI(4,5)P2 in the localization of the HIV-1 structural polyprotein Gag to the plasma membrane.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
lipid transfer proteins;cholesterol depletion;PI(4,5)P2;protein function;human disorders;plasma membrane;potassium channels;lyosomal cholesterol;ciliary membrane;thermoTRPs;epithelial sodium channel;lipid transport proteins;cholesterol extraction;lysosomes;peroxisomes;N-terminal;Actin nucleation;Intercellular trafficking;HIV assembly;HIV-1
