Reproducibility in Biomedical Research

Reproducibility in Biomedical Research

Epistemological and Statistical Problems and the Future

Montgomery Jr., Erwin B.

Elsevier Science Publishing Co Inc

04/2024

462

Mole

Inglês

9780443138294

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1. Introduction
2. The Problem of Irreproducibility
3. Validity of Biomedical Science, Reproducibility, and Irreproducibility
4. The Logic of Certainty versus the Logic of Discovery
5. The Logic of Probability and Statistics
6. Causation, Process Metaphor, and Reductionism
7. Case Studies in Clinical Biomedical Research 8. Case Studies in Basic Biomedical Research
9. Case Studies in Computational Biomedical Research
10. Case Studies in Machine Learning Artificial Intelligence (AI)
11. Reproducibility of translation from biomedical research to clinical care
12. Chaotic and Complex Systems, Statistics, and Far-from-Equilibrium Thermodynamics
13. The Nature of the Fundamental Challenges to Reproducibility in any Knowledge Discipline
14. Epilogue
15. Appendix: Types of lack of reproducibilityility
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Biomedical research; reproducibility; replicability; case studies; machine learning; Artificial Intelligence; AI; translational research; logical reasoning; reasoning in probability and statistics; nonlinear science