Glycosignals in Cancer

Glycosignals in Cancer

Molecular Assembly and Recognition

Furukawa, Koichi; Fukuda, Minoru

Springer Verlag, Singapore

03/2024

238

Mole

9789811977343

15 a 20 dias

Descrição não disponível.
Part I. Search for novel tumor epitopes related to carbohydrates.- Chapter 1.1. The ganglioside structures: chemistry and biochemistry.- Chapter 1.2. Fucosylated proteins as cancer biomarkers.- Part II. Assembly of glycoconjugates.- Chapter 2.1. Siglec-7 and synthetic sialylpolymer.- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis.- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer.- Part III. Signaling pathways modulated by glycosylation.- Chapter 3.1. Significance of FUT8in pancreatic cancer and others.- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells.- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules.- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells.- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction.- Part V. Clinical trials targeting glycosignals.- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.
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Glycosylation;Cancer;Signal;Sugar chain;Carbohydrate;Therapy;Cancer-associated antigens;lectins