Vascular Mechanobiology in Physiology and Disease

Preface.- Hemodynamics and vascular remodeling.- The biomechanics of venous remodeling.- New kids on the block: the emerging role of YAP/TAZ in vascular cell mechano-transduction.- GPCRs und flow and pressure.- Biomechanics in small artery remodeling.- Contributions of wall stretch and shear stress to vascular regulation: Molecular mechanisms of homeostasis and expansion.- Mechanobiology of lymphatic vessels.- Hemodynamic control of endothelial cell fates in development.- Mechanical regulation of epigenetic modifications in vascular biology and pathobiology.- Mechanosensing and mechanotransduction in pulmonary hypertension.- Mechanobiology of arterial hypertension.- Mechanobiology of atherosclerosis.- Exploitation of vascular mechanobiology for cardiovascular therapy.

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• Ciências da vida: temas gerais
• Biotecnologia
• Fisiologia
• Medicina cardiovascular

mechanobiology;physiology;pathophysiology;shear stress;haemodynamics;vascular cells;biomechanics of venous remodeling;mechanosensing;mechanotransduction;hypertension;biomechanical forces;mechanoperception;epigenetics;vascular biology;vascular grwoth;lymphatic vessels;atherosclerosis