Transcriptional Regulation by Neuronal Activity
portes grátis
Transcriptional Regulation by Neuronal Activity
To the Nucleus and Back
Dudek, Serena M.; Saha, Ramendra N.
Springer International Publishing AG
11/2024
595
Dura
9783031685491
15 a 20 dias
Descrição não disponível.
Section 1: Activity-regulated Transcription: Getting to the Nucleus.- Fos/AP-1 as an exemplar for the study of neuronal activity-dependent gene regulation.- Calcium signaling to the nucleus.- Protein transport from synapse-to-nucleus and the regulation of gene expression.- Gene regulation by nuclear calcium and its antagonism by NMDAR/TRPM4 signaling.- Chemoelectric signaling, protein translocation and neuronal transcription.- Section 2: Activity-regulated Transcription: Epigenetic Regulation.- Histone variants in neuronal transcription and behavioral regulation.- Genome and epigenome engineering approaches to studying neuronal activity-dependent transcriptional enhancers.- Higher-order genome organization in the control of neuronal identity and neural circuit plasticity.- Chromatin remodelers in neuronal gene transcription.- Section 3: Activity-regulated Transcription: Role in Nervous System Function.- Nature and nurture converge in the nucleus to regulate activity-dependent neuronal development.- Roles for the MEF2 transcription factors in synapse and circuit development and plasticity.- Activity-related transcription: role in addiction.- Epigenetic priming of activity-dependent transcription in drug addiction.- Molecular intersection of activity-dependent gene expression and behavior: the transcriptomic signature of long-term memory consolidation.- Perturbations to stimulus-dependent gene activity patterns in neurodegenerative disorders.- Section 4: New Tools to Study and Use Activity-regulated Transcription.- Genome editing technologies for investigation of activity dependent transcription.- Imaging activity dependent gene expression in neurons: RNA tagging technologies.- Optogenetic approaches to study IEG activation.- New Genome-wide Technologies to Study Activity-regulated Transcription.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Nervous System;Neuroscience;gene expression;gene regulation;gene transcription;neurons;plasticity;synaptic plasticity;intercellular signaling;calcium-dependant signaling;synapse-to-nucleus signaling;chromatin remodelers;enhancers;histone modifications;role in sleep;role in addiction;role in learning and memory;role in development
Section 1: Activity-regulated Transcription: Getting to the Nucleus.- Fos/AP-1 as an exemplar for the study of neuronal activity-dependent gene regulation.- Calcium signaling to the nucleus.- Protein transport from synapse-to-nucleus and the regulation of gene expression.- Gene regulation by nuclear calcium and its antagonism by NMDAR/TRPM4 signaling.- Chemoelectric signaling, protein translocation and neuronal transcription.- Section 2: Activity-regulated Transcription: Epigenetic Regulation.- Histone variants in neuronal transcription and behavioral regulation.- Genome and epigenome engineering approaches to studying neuronal activity-dependent transcriptional enhancers.- Higher-order genome organization in the control of neuronal identity and neural circuit plasticity.- Chromatin remodelers in neuronal gene transcription.- Section 3: Activity-regulated Transcription: Role in Nervous System Function.- Nature and nurture converge in the nucleus to regulate activity-dependent neuronal development.- Roles for the MEF2 transcription factors in synapse and circuit development and plasticity.- Activity-related transcription: role in addiction.- Epigenetic priming of activity-dependent transcription in drug addiction.- Molecular intersection of activity-dependent gene expression and behavior: the transcriptomic signature of long-term memory consolidation.- Perturbations to stimulus-dependent gene activity patterns in neurodegenerative disorders.- Section 4: New Tools to Study and Use Activity-regulated Transcription.- Genome editing technologies for investigation of activity dependent transcription.- Imaging activity dependent gene expression in neurons: RNA tagging technologies.- Optogenetic approaches to study IEG activation.- New Genome-wide Technologies to Study Activity-regulated Transcription.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Nervous System;Neuroscience;gene expression;gene regulation;gene transcription;neurons;plasticity;synaptic plasticity;intercellular signaling;calcium-dependant signaling;synapse-to-nucleus signaling;chromatin remodelers;enhancers;histone modifications;role in sleep;role in addiction;role in learning and memory;role in development
