Targeted Metallo-Drugs

Targeted Metallo-Drugs

Design, Development, and Modes of Action

Farkas, Etelka; Marmion, Celine J.

Taylor & Francis Ltd

12/2024

370

Mole

9781032223537

Pré-lançamento - envio 15 a 20 dias após a sua edição

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Chapter 1 Metal-Based Prodrugs Activated by Cancer-Specific Stimuli by Martijn Dijkstra, Hemma Schueffl, Isabella Poetsch, Petra Heffeter, and Christian R. Kowol. Chapter 2 Light-Activated Drugs for Photodynamic and Photoactivated Therapy by Dmytro Havrylyuk, Austin Hachey, and Edith Glazer. Chapter 3 Mitochondria as a Metallo-Drug Target for Therapeutic Purposes by Andrea Erxleben. Chapter 4 Transition Metal-Based Antiviral Agents against SARS-CoV-2 and Other Pathogenic Viruses by Maria Gil-Moles and Ingo Ott. Chapter 5 Exploiting the Chemical Diversity of Metal Compounds as a Source of Novel Anti-COVID-19 Drugs by Damiano Cirri, Tiziano Marzo, Carlo Marotta, Alessandro Pratesi, and Luigi Messori . Chapter 6 Evaluating the Potential of Novel Metal-Based Drugs for Treating Drug-Resistant Bacteria by Andris Evans and Kevin Kavanagh. Chapter 7 Prospective Metallo-Drugs Including Bioactive Compounds: Selection of Co-Ligands to Tune Biological Activity against Neglected Tropical Diseases by Dinorah Gambino and Lucia Otero. Chapter 8 Challenges in Targeting Cyanide Poisoning: Advantages in Exploiting Metal Complexes in Its Treatment by Sigridur G. Suman. Chapter 9 Advanced Microscopy Methods for Elucidating the Localization of Metal Complexes in Cancer Cells by Johannes Karges and Nils Metzler-Nolte.Chapter 10 Metalloproteomics: A Powerful Technique for Metals in Medicine by Tiffany Ka-Yan Ip, Ying Zhou, Hongyan Li, and Hongzhe Sun. Chapter 11 Metal-Based Nanoclusters for Biomedical Applications by Edit Csapo. Chapter 12 Radiometals in Molecular Imaging and Therapy by Izabela Cieszykowska, Wioletta Wojdowska, Dariusz Pawlak, and Renata Mikolajczak.
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Bioinorganic chemistry;Targeted metallodrugs designed to overcome anti-microbial resistance;Anti-cancer and anti-fungal agents;Chemotherapeutics;Drug design and discovery;Nanoparticles and nanoclusters;Mitochondrial Pyruvate Carrier;Sodium Stibogluconate;Middle East Respiratory Syndrome Coronavirus;Ranitidine Bismuth Citrate;TrxR Inhibition;Transition Metal Complexes;Colloidal Bismuth Subcitrate;Bismuth Subcitrate;XRF Imaging;Cruzi Activity;Cyanide Blood Concentration;NHC Ligand;RBD;Protein Protein Interaction Network;Bioactive Ligand;Luminescence Lifetime;ROS Level;Confocal Laser Scanning Microscopy Images;Important Biological Target;Titanocene Dichloride;Inorganic Drugs;3CL Pro;Cyanide Poisoning;NB4 APL Cell;Antimicrobial Resistance