Retinoic Acids in Cancer Therapy

1. Molecular structure and biological properties of all-trans retinoic acid
2. Emerging frontiers in drug development of all-trans retinoic acid and its derivatives
3. Cellular and molecular determinants of all trans retinoic acid sensitivity in different cancers
4. Apoptosis, autophagy, and unfolded protein response and their impact on all-trans retinoic acid induced toxicity in cancer cells
5. Mechanisms of resistance to all-trans retinoic acid and use of multi-target-directed ligand to fight against resistance
6. Nanocarrier systems for targeted delivery of all-trans retinoic acid: design and mechanisms
7. Advanced delivery systems for all-trans retinoic acid: challenges and opportunities in pharmacokinetics and bioavailability
8. Mechanisms of sensitivity, resistance, and methods of delivery
9. Efficiency of all-trans retinoic acid on gastric cancer
10. All-trans retinoic acid and its role in glioblastoma therapy
11. All-trans retinoic acid and vitamin A in neurodegeneration: from oncology to neuroprotection
12. Efficiency of all-trans retinoic acid in liver cancer
13. Efficiency of all-trans retinoic acid on colon cancer
14. Retinoic acids in head and neck cancer therapy: mechanisms of sensitivity, resistance, and methods of delivery
15. Role of artificial intelligence and machine learning in predicting all-trans retinoic acid treatment outcomes

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• Oncologia
• Farmacologia

All Trans Retinoic Acid; ATRA; retinoic acid; retinoid; anticancer efficacy; apoptosis; autophagy; stem cell