Resistance in Hematologic Malignancies and Cancer

Resistance in Hematologic Malignancies and Cancer

Breier, Albert; Messingerova, Lucia

Elsevier Science Publishing Co Inc

11/2024

326

Dura

9780443217906

15 a 20 dias

Descrição não disponível.
1. Drug classification for treatment Hematological Malignancies
2. Reduce drug uptake in development of resistance
3. The Role of Enhanced Drug Efflux in Drug Resistance
4. MicroRNAs and other non-coding RNA species in diagnostics, prognostics and therapy response of blood cancers.
5. Switching between autophagy and apoptosis pro-survival and pro-death balance in leukemia cells
6. The role of UPR signaling pathways in cancer cell resistance to chemotherapy
7. Altered cell cycle regulation
8. Deregulation of drug metabolizing enzymes and transporters in cancer via the aryl hydrocarbon receptor
9. Immune system in resistance prediction
10. Mechanisms of resistance of antibody-drug conjugates - obstacles to overcome
11. Resistance to Chimeric Antigen Receptor T Cells (CAR-T)
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ABC transporters; Antibody-drug conjugate; Antitumor drugs; Apoptosis; Aryl hydrocarbon receptor; Autophagy; Cancer; Cancer chemoresistance; Cancer immunotherapy; Cell cycle; Cell death; Cell therapy; Chemoresistance; Chemotherapy; Chimeric antigen receptor T cell; Classification; Combination treatment; Cytotoxic payload; Diagnostics; Dormancy; Drug efflux; Drug influx; Drug resistance; Drug tolerance; Drug transporters; Endoplasmic reticulum; Genetic variants; Hematologic malignancies; Hematological malignancies; Hematological malignancy; Imaging; Immune checkpoint blockage; Immunomodulation; Immunotherapy; Leukemia; Mechanisms of resistance; Membrane barriers; Membrane fluidity and permeability; microRNAs; Multidrug resistance; Noncoding RNAs; Prognostics; Radiotherapy; Resistance; Resistance mechanisms; Solute carriers transporters; Strategies in management; Stress; Therapeutic strategies; Tumor microenvironment; Unfolded protein response; Xenobiotic-metabolizing enzymes