Purinergic Receptors and their Modulators
Purinergic Receptors and their Modulators
Supuran, Claudiu T.; Colotta, Vittoria
Springer International Publishing AG
09/2023
354
Dura
Inglês
9783031397240
15 a 20 dias
Descrição não disponível.
Once upon a time adenosine and its receptors. Historical survey and perspectives as potential targets for therapy in human diseases.- Adenosine receptor ligands, probes and functional conjugates: A twenty-year history of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines (PTP).- Adenosine receptor ligands as potential therapeutic agents for impaired wound healing and fibrosis.- Adenosine A2A receptor antagonists: chemistry, SARs, modeling studies and therapeutic potential.- A2B Adenosine Receptor as a new and attractive target to treat brain ischemia or demyelination.- A3 adenosine receptor ligands: from discovery to clinical trials.- Bifunctional tools to study adenosine receptors.- Allosteric modulators of adenosine receptors.- New computational approaches in inspecting adenosine receptor-ligand recognition process.- P2X4 receptors in immunity and inflammation.- CD73 inhibitors as antitumor agents.- Bacterial ectonucleotidases- underexplored antibacterial targets.
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CD73 inhibitors;A3 adenosine receptor ligands;Purinergic Receptors;Purinergic Signalling;P1 and P2 receptors
Once upon a time adenosine and its receptors. Historical survey and perspectives as potential targets for therapy in human diseases.- Adenosine receptor ligands, probes and functional conjugates: A twenty-year history of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines (PTP).- Adenosine receptor ligands as potential therapeutic agents for impaired wound healing and fibrosis.- Adenosine A2A receptor antagonists: chemistry, SARs, modeling studies and therapeutic potential.- A2B Adenosine Receptor as a new and attractive target to treat brain ischemia or demyelination.- A3 adenosine receptor ligands: from discovery to clinical trials.- Bifunctional tools to study adenosine receptors.- Allosteric modulators of adenosine receptors.- New computational approaches in inspecting adenosine receptor-ligand recognition process.- P2X4 receptors in immunity and inflammation.- CD73 inhibitors as antitumor agents.- Bacterial ectonucleotidases- underexplored antibacterial targets.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.