Proteostasis and Proteolysis

Preface. Contributors. The Editors. Ribosomal Pauses during Translation and Proteostasis. Protein Folding and Misfolding: Deciphering Mechanisms of Age-Related Diseases. Transcriptional Regulation of Proteostatic Mechanisms. MicroRNAs as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging. mRNA Granules and Proteostasis in Aging and Age-Related Diseases. Phospholipids and the Unfolded Protein Response. Ubiquitin Ligases Involved in Progeroid Syndromes and Age-Associated Pathologies. Role of SUMOylation in Neurodegenerative Diseases and Inflammation. NEDD8 and Oxidative Stress. Structure, Function and Regulators of the 20S Proteasome. Cellular Responses to Proteasome Impairment. Proteasome Fate in Aging and Proteinopathies. The Proteasomal System in Cancer. Proteostasis and Skin Aging. Reactive Oxygen Species and Protein Homeostasis in Skeletal Muscle Regeneration. Protein Degradation in Cardiac Health and Disease. Autophagy in Aging and Oxidative Stress. Autophagy in Aging and Longevity Exemplified by the Aging Heart. Index.

Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.

• Química orgânica
• Biologia molecular
• Medicina pré-clínica: ciências básicas
• Bioquímica

protein quality control;neurodegenerative mechanisms;skeletal muscle aging;unfolded protein response;oxidative stress pathways;age-related disease models;cellular protein degradation mechanisms