Protein Misfolding in Neurodegenerative Diseases

Protein Misfolding in Neurodegenerative Diseases

Singh, Sandeep Kumar; Gogia, Neha; Devarunda Jaganath, Vidyadhara

Elsevier Science Publishing Co Inc

03/2025

574

Mole

Inglês

9780443187162

15 a 20 dias

Descrição não disponível.
1. Maintenance of balanced proteome homeostasis
2. Determinants of protein misfolding, aggregation in neuronal cell death
3. Classification, structure, and function of protein aggregates in proteinopathies
4. Protein aggregation and cellular and molecular mechanisms in neurodegenerative disease
5. Advances in methods to detect and study protein aggregation
6. Organelle specific protein quality control
7. Molecular chaperones and co-chaperones in proteostasis
8. The ubiquitin-Proteasome System (UPS) and Autophagy lysosomal proteolytic pathways
9. Alterations in protein quality control
10. Alternate mechanisms to maintain proteome homeostasis
11. Advances in developing novel therapeutics, strategies, approaches and use of emerging techniques
12. Challenges in translating laboratory findings to drug development
13. Advancements in drug delivery technologies for protein misfolding diseases
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<p>Protein misfolding; proteinopathies; cellular and molecular mechanisms; neurodegeneration; neurodegenerative diseases; <i>in vivo</i> model; <i>in vitro</i> model; biomarkers; therapeutics</p>