Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine
portes grátis
Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine
Kloc, Malgorzata; Kubiak, Jacek Z.
Springer International Publishing AG
11/2022
663
Dura
Inglês
9783031065729
15 a 20 dias
1172
Descrição não disponível.
Part I. Genome Architecture, Evolution, and Cell Fate.- Chapter 1. Networks and Islands of Genome Nano-Architecture and their Potential Relevance for Radiation Biology (A Hypothesis and Experimental Verification Hints).- Chapter 2. A Unified Genomic Mechanism of Cell-Fate Change.- Chapter 3. Alterations to Genome Organisation in Stem Cells, Their Differentiation and Associated Diseases.- Chapter 4. How Genomes Emerge, Function, and Evolve: Living Systems Emergence - Genotype-Phenotype-Multilism - Genome/Systems Ecology.- Chapter 5. Integrating Multimorbidity into a Whole-Body Understanding of Disease Using Spatial Genomics.- Part II. Chromosomes and Chromatin Architecture and Dynamics.- Chapter 6. Mitotic Antipairing of Homologous Chromosomes.- Chapter 7. CENP-A, a Histone H3 Variant with Key Roles in Centromere Architecture in Healthy and Diseased States.- Chapter 8. Scaling Relationship in Chromatin as a Polymer.- Chapter 9. Chromatin Dynamics during Entry toQuiescence and Compromised Functionality in Cancer Cells.- Chapter 10. Functional Aspects of Sperm Chromatin Organization.- Part III. Mechanosensitive and Epigenetic Regulators of Gene Expression and Chromatin Organization.- Chapter 11. The LINC Complex Assists the Nuclear Import of Mechanosensitive Transcriptional Regulators.- Chapter 12. Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Cell and Tissue Structure, Function, and Phenotype.- Chapter 13. Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Fidelity of Mechanisms Governing the Cell Cycle.- Chapter 14. Histone Modifications in Mouse Pronuclei and Consequences for Embryo Development.- Part IV. Nucleus, Nucleolus, and Nucleolar Organizer Architecture.- Chapter 15. Nuclear Architecture in the Nervous System.- Chapter 16. Nuclear Morphological Abnormalities in Cancer: A Search for Unifying Mechanisms.- Chapter 17. Nuclear Organization in Response to Stress: A Special Focus on Nucleoli.- Chapter 18. Simulation of Different Three-Dimensional Models of Whole Interphase Nuclei Compared to Experiment - A Consistent Scale-Bridging Simulation Framework for Genome Organization.- Chapter 19. Nucleolar Organizer Regions as Transcription-Based Scaffolds of Nucleolar Structure and Function.- Chapter 20. A Transient Mystery: Nucleolar Channel Systems.- Part V. Nuclear Actin Role in Polarization, Genome Organization, and Gene Expression.- Chapter 21. Cellular Polarity Transmission to the Nucleus.- Chapter 22. The Role of Nuclear Actin in Genome Organization and Gene Expression Regulation During Differentiation.- Chapter 23. Nuclear Actin Dynamics in Gene Expression, DNA Repair, and Cancer.
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Cell Nucleus;Chromosomal Architecture;Chromatin Organization;Genomic Architecture;Gene Expression;Nucleoskeleton;Nuclear Architecture;Nuclear Condensation;Nuclear Organization;Nuclear Structure
Part I. Genome Architecture, Evolution, and Cell Fate.- Chapter 1. Networks and Islands of Genome Nano-Architecture and their Potential Relevance for Radiation Biology (A Hypothesis and Experimental Verification Hints).- Chapter 2. A Unified Genomic Mechanism of Cell-Fate Change.- Chapter 3. Alterations to Genome Organisation in Stem Cells, Their Differentiation and Associated Diseases.- Chapter 4. How Genomes Emerge, Function, and Evolve: Living Systems Emergence - Genotype-Phenotype-Multilism - Genome/Systems Ecology.- Chapter 5. Integrating Multimorbidity into a Whole-Body Understanding of Disease Using Spatial Genomics.- Part II. Chromosomes and Chromatin Architecture and Dynamics.- Chapter 6. Mitotic Antipairing of Homologous Chromosomes.- Chapter 7. CENP-A, a Histone H3 Variant with Key Roles in Centromere Architecture in Healthy and Diseased States.- Chapter 8. Scaling Relationship in Chromatin as a Polymer.- Chapter 9. Chromatin Dynamics during Entry toQuiescence and Compromised Functionality in Cancer Cells.- Chapter 10. Functional Aspects of Sperm Chromatin Organization.- Part III. Mechanosensitive and Epigenetic Regulators of Gene Expression and Chromatin Organization.- Chapter 11. The LINC Complex Assists the Nuclear Import of Mechanosensitive Transcriptional Regulators.- Chapter 12. Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Cell and Tissue Structure, Function, and Phenotype.- Chapter 13. Epigenetic-Mediated Regulation of Gene Expression for Biological Control and Cancer: Fidelity of Mechanisms Governing the Cell Cycle.- Chapter 14. Histone Modifications in Mouse Pronuclei and Consequences for Embryo Development.- Part IV. Nucleus, Nucleolus, and Nucleolar Organizer Architecture.- Chapter 15. Nuclear Architecture in the Nervous System.- Chapter 16. Nuclear Morphological Abnormalities in Cancer: A Search for Unifying Mechanisms.- Chapter 17. Nuclear Organization in Response to Stress: A Special Focus on Nucleoli.- Chapter 18. Simulation of Different Three-Dimensional Models of Whole Interphase Nuclei Compared to Experiment - A Consistent Scale-Bridging Simulation Framework for Genome Organization.- Chapter 19. Nucleolar Organizer Regions as Transcription-Based Scaffolds of Nucleolar Structure and Function.- Chapter 20. A Transient Mystery: Nucleolar Channel Systems.- Part V. Nuclear Actin Role in Polarization, Genome Organization, and Gene Expression.- Chapter 21. Cellular Polarity Transmission to the Nucleus.- Chapter 22. The Role of Nuclear Actin in Genome Organization and Gene Expression Regulation During Differentiation.- Chapter 23. Nuclear Actin Dynamics in Gene Expression, DNA Repair, and Cancer.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
