Natural Product-based Synthetic Drug Molecules in Alzheimer's Disease
portes grátis
Natural Product-based Synthetic Drug Molecules in Alzheimer's Disease
Therapeutic & Theranostic Agents
Modi, Gyan Prakash; Sharma, Abha
Springer Verlag, Singapore
12/2023
447
Dura
Inglês
9789819960378
15 a 20 dias
Descrição não disponível.
Section 1: Introduction of Alzheimer's Disease.- Chapter 1: Alzheimer's disease and drug targets.- Chapter 2: Oxidative stress and metals in Alzheimer's disease.- Chapter 3: Neuroinflammation in Alzheimer's disease.- Section 2: Biomarkers and Diagnosis in Alzheimer's Disease.- Chapter 4: Biomarkers of Alzheimer's disease.- Chapter 5: Naturally inspired fluorescent organic molecules as diagnostic and theranostic tools in Alzheimer's disease.- Chapter 6: Nanostructure-based molecules as diagnostic and theranostic tools in AD.- Section 3: Drug derivatives: A strategy for new multifunctional drug development for Alzheimer's Disease.- Chapter 7: Approved cholinesterase inhibitors-based derivatives: Synthesis and their biological evaluation.- Chapter 8: Memantine-based derivatives: Synthesis and their biological evaluation.- Section 4: Natural molecules inspired novel derivatives for Alzheimer's Disease.- Chapter 9: Huperzine-based derivatives: Design, synthesis, and anti-Alzheimer activity.- Chapter 10: Polyphenol: Development of polyphenol-inspired derivatives targeting pathological factors of AD.- Chapter 11: Flavonoid-based derivatives for modulating various targets of Alzheimer's disease.- Chapter 12: Vitamin-based derivatives for the management of Alzheimer's disease.- Section 5: Metal dyshomeostasis: A hypothesis for developing drugs for the treatment of Alzheimer's disease.- Chapter 13: Metal chelators as a potential therapeutic agent for Alzheimer's disease.- Chapter 14: Ferroptosis modulators: A potential therapeutic target in Alzheimer's disease.- Section 6. Natural products/Synthetic molecules as epigenetic modulators in Alzheimer's disease.- Chapter 15. Sirtuin modulator: Design, synthesis, and biological evaluation.- Chapter 16. Histone deacetylase Inhibitors: Design, synthesis, and biological evaluation.
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Alzheimer's disease;Antioxidant;Natural molecules;Biomarkers;Multi-target ligand
Section 1: Introduction of Alzheimer's Disease.- Chapter 1: Alzheimer's disease and drug targets.- Chapter 2: Oxidative stress and metals in Alzheimer's disease.- Chapter 3: Neuroinflammation in Alzheimer's disease.- Section 2: Biomarkers and Diagnosis in Alzheimer's Disease.- Chapter 4: Biomarkers of Alzheimer's disease.- Chapter 5: Naturally inspired fluorescent organic molecules as diagnostic and theranostic tools in Alzheimer's disease.- Chapter 6: Nanostructure-based molecules as diagnostic and theranostic tools in AD.- Section 3: Drug derivatives: A strategy for new multifunctional drug development for Alzheimer's Disease.- Chapter 7: Approved cholinesterase inhibitors-based derivatives: Synthesis and their biological evaluation.- Chapter 8: Memantine-based derivatives: Synthesis and their biological evaluation.- Section 4: Natural molecules inspired novel derivatives for Alzheimer's Disease.- Chapter 9: Huperzine-based derivatives: Design, synthesis, and anti-Alzheimer activity.- Chapter 10: Polyphenol: Development of polyphenol-inspired derivatives targeting pathological factors of AD.- Chapter 11: Flavonoid-based derivatives for modulating various targets of Alzheimer's disease.- Chapter 12: Vitamin-based derivatives for the management of Alzheimer's disease.- Section 5: Metal dyshomeostasis: A hypothesis for developing drugs for the treatment of Alzheimer's disease.- Chapter 13: Metal chelators as a potential therapeutic agent for Alzheimer's disease.- Chapter 14: Ferroptosis modulators: A potential therapeutic target in Alzheimer's disease.- Section 6. Natural products/Synthetic molecules as epigenetic modulators in Alzheimer's disease.- Chapter 15. Sirtuin modulator: Design, synthesis, and biological evaluation.- Chapter 16. Histone deacetylase Inhibitors: Design, synthesis, and biological evaluation.
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