Immuno-oncology and immunotherapy Part B

1. Multiparametric flow cytometry study of human MDSCs
Luis de la Cruz-Merino and Victor Sanchez-Margalet Sr.
2. In vitro screening methods of novel immune checkpoint inhibitors related to T cell infiltration and anti-PD-1 resistance
Yanfeng Gao, Zhuouying He, Xiuman Zhou and Youmei Xiao
3. Machine learning approach to assess brain metastatic burden in preclinical models
Romina Goldszmid
4. Cytofluorometric analysis of the maturation and activation of bone marrow-derived dendritic cells to assess immunogenic cell death
Dmitri Krysko, Faye Naessens, Iuliia Efimova and Mariia Saviuk
5. 3D agar colony inhibition assays to functionally evaluate HER2-targeting antibodies against human cancer cells elicited by vaccination in mice
Pier-Luigi Lollini, Francesca Ruzzi, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Chiara Cappello, Olga Maria Pittino, Patrizia Nanni and Arianna Palladini
6. Spatial immunophenotyping of FFPE tissues by imaging mass cytometry
Barbara Maier
7. Processing human colon cancer specimens for in vitro cytotoxicity assays
Sofia Mensurado Santos, Rafael Blanco Dominguez, Bruno Silva-Santos, Mariana Carreira and Leandro Barros
8. A xenograft model of metastatic colon cancer
Sofia Mensurado Santos and Rafael Blanco Dominguez
9. A preclinical model of hepatic metastasis to instruct effetive treatment modalities
Anna Mondino, Citro Antonio, Lorenzo Piemonti, Arianna Pocaterra, Chiara Gnasso, Tamara Canu, Anna Tosi, Antonio Rosato and Antonio Esposito
10. Myeloid-derived suppressor cells: Identification and function
Lorenzo Moretta, Nicola Tumino, Maria Teresa Bilotta and Paola Vacca
11. Measuring the impact of therapy-induced senescence on NK cell phenotypes in cancer
Marcus Ruscetti, Shreya Chowdhury, Katherine Murphy, Chaitanya Parikh, Kelly DeMarco and Lin Zhou
12. Selective expansion of anti-tumour innate lymphocytes in long-term cultures after a single BCG pulse
Mar Vales-Gomez

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• Biologia do desenvolvimento
• Biologia Celular (citologia)
• Oncologia
• Biologia molecular

3D growth; Animal model; Antibodies; Antigen presenting cells; Anti-tumor immune response; Apoptosis; BCG; Cancer; Cancer immunotherapy; Cell therapy; Chemotherapy; Co-culture assays; Collagen; Colorectal cancer; Conjugated antibody; Cytokine-release assays; Cytotoxic assay; DDR1; Degranulation; Dendritic cells; Extracellular matrix; Flow cytometry; Growth inhibition; Hepatic metastasis; HER-2; High-dimensional imaging; Imaging mass cytometry; Immunology; Immunomodulatory cells; Immunophenotype; Immunotherapy; In vitro expansion; In vivo tumor monitoring; Intracaecal; KeywordImmune checkpoint inhibitors; Magnetic resonance imaging; Metastasis; Migration assays; Mouse model; Mouse models; Multiplex imaging; Multiplex immunofluorescence; Myeloid-derived suppressor cells; Myeloid-derived suppressor cells (MDSCs); Natural Killer cells; NK cells; Orthotopic; Pancreatic cancer; Pancreatic ductal adenocarcinoma; Phenotypic analysis; Primary tumors; RAS targeted therapies; SASP; Senescence; Soft-agar; Specific lysis; Surgery; T cell migration; Tissue digestion; Tumor immunology; Tumor implantation; Tumor microenviornment; Tumor microenvironment; Tumor spheres; Xenograft; ?? T cells