Handbook of Pharmacokinetics and Toxicokinetics
portes grátis
Handbook of Pharmacokinetics and Toxicokinetics
Boroujerdi, Mehdi
Taylor & Francis Ltd
12/2024
752
Mole
9781032197470
Pré-lançamento - envio 15 a 20 dias após a sua edição
Descrição não disponível.
Chapter 1. Pharmacokinetics and Toxicokinetics. Chapter 2. PK-TK Conisderations of Auricular (Optic) - Buccal/Sublingual and Ocular/Ophthalmic Routes of Administration. Chapter 3. PK-TK Considerations of Nasal, Pulmonary and Oral Routes of Administration. Chapter 4. PK-TK Considerations of Intraarterial - Intramuscular Intraperitoneal - Intravenous - and Subcutaneous Routes of Administration. Chapter 5. PK-TK Considerations of Transdermal - Intradermal - and Intraepidermal Routes of Administration. Chapter 6. PK-TK Considerations of Rectal - Vaginal - Intraovarian Routes of Administration. Chapter 7. PK-TK Considerations of Absorption Mechanisms and Rate Equations. Chapter 8. PK-TK Considerations of Distribution Mechanisms and Rate Equations. Chapter 8. PK-TK Considerations of Metabolism Biotransformation of Xenobiotics Mechanisms and Rate Equations. Chapter 10. PK-TK Considerations of Renal Function and Elimination of Xenobiotics Estimation of Parameters and Constants. Chapter 11. Elimination Rates & Clearances (Excretion + Metabolism). Chapter 12. Approaches in PK-PD and TK-TD Mathematical Modeling. Chapter 13. Practical Applications of PK/TK Models Instantaneous Exposure to Xenobiotics Single Intravenous Bolus Injection. Chapter 14. Practical Applications of PK/TK Models Continuous Zero-Order Exposure to Xenobiotics Intravenous Infusion. Chapter 15. Practical Applications of PK/TK Models First-order Absorption via Extravascular Routes Oral Administration. Chapter 16. Practical Application of PK/TK Models Multiple Dosing Kinetics. Chapter 17. Biopharmaceutics Provisions, Dynamics, and Classifications Mechanistic Absorption Models. Chapter 18. Bioavailability, Bioequivalence and Biosimilarity. Chapter 19. Quantitative Extrapolations Cross-Species Extrapolation Low-Dose Extrapolation. Chapter 20. Practical Application of PK/TK Models Population Pharmacokinetics/Toxicokinetics. Chapter 21. Practical Application of PK/TK Models Preclinical PK/TK and Clinical Trials. Chapter 22. Adjustment of Dosage Regimen Renal Impairment, Liver Diseases, Pregnancy.
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Pharmacokinetics (PK);Pharmacodynamics (PD);Toxicokinetics (TK);Toxicodynamics (TD);Xenobiotics;Sustainable development goals;Mathematical and statistical concepts;Bioavailability;Bioequivalence;Biosimilar evaluations;Plasma Concentration;Total Body Clearance;Plasma Concentration Time Curve;Normal Renal Function;Iv Bolus;Excretion Rate Constants;Central Compartment;Peripheral Compartment;Initial Plasma Concentration;Average Steady State Plasma Concentration;Distribution Rate Constants;Dosage Form;Urine Data;Steady State Plasma Level;TK Parameter;Ich;Hybrid Rate Constants;ADME;Steady State Plasma Concentration;Non-compartmental Analysis;Maximum Plasma Concentration;Dosing Interval;Plasma Concentration Time Profile;Clavulanic Acid;Ideal Body Weight
Chapter 1. Pharmacokinetics and Toxicokinetics. Chapter 2. PK-TK Conisderations of Auricular (Optic) - Buccal/Sublingual and Ocular/Ophthalmic Routes of Administration. Chapter 3. PK-TK Considerations of Nasal, Pulmonary and Oral Routes of Administration. Chapter 4. PK-TK Considerations of Intraarterial - Intramuscular Intraperitoneal - Intravenous - and Subcutaneous Routes of Administration. Chapter 5. PK-TK Considerations of Transdermal - Intradermal - and Intraepidermal Routes of Administration. Chapter 6. PK-TK Considerations of Rectal - Vaginal - Intraovarian Routes of Administration. Chapter 7. PK-TK Considerations of Absorption Mechanisms and Rate Equations. Chapter 8. PK-TK Considerations of Distribution Mechanisms and Rate Equations. Chapter 8. PK-TK Considerations of Metabolism Biotransformation of Xenobiotics Mechanisms and Rate Equations. Chapter 10. PK-TK Considerations of Renal Function and Elimination of Xenobiotics Estimation of Parameters and Constants. Chapter 11. Elimination Rates & Clearances (Excretion + Metabolism). Chapter 12. Approaches in PK-PD and TK-TD Mathematical Modeling. Chapter 13. Practical Applications of PK/TK Models Instantaneous Exposure to Xenobiotics Single Intravenous Bolus Injection. Chapter 14. Practical Applications of PK/TK Models Continuous Zero-Order Exposure to Xenobiotics Intravenous Infusion. Chapter 15. Practical Applications of PK/TK Models First-order Absorption via Extravascular Routes Oral Administration. Chapter 16. Practical Application of PK/TK Models Multiple Dosing Kinetics. Chapter 17. Biopharmaceutics Provisions, Dynamics, and Classifications Mechanistic Absorption Models. Chapter 18. Bioavailability, Bioequivalence and Biosimilarity. Chapter 19. Quantitative Extrapolations Cross-Species Extrapolation Low-Dose Extrapolation. Chapter 20. Practical Application of PK/TK Models Population Pharmacokinetics/Toxicokinetics. Chapter 21. Practical Application of PK/TK Models Preclinical PK/TK and Clinical Trials. Chapter 22. Adjustment of Dosage Regimen Renal Impairment, Liver Diseases, Pregnancy.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Pharmacokinetics (PK);Pharmacodynamics (PD);Toxicokinetics (TK);Toxicodynamics (TD);Xenobiotics;Sustainable development goals;Mathematical and statistical concepts;Bioavailability;Bioequivalence;Biosimilar evaluations;Plasma Concentration;Total Body Clearance;Plasma Concentration Time Curve;Normal Renal Function;Iv Bolus;Excretion Rate Constants;Central Compartment;Peripheral Compartment;Initial Plasma Concentration;Average Steady State Plasma Concentration;Distribution Rate Constants;Dosage Form;Urine Data;Steady State Plasma Level;TK Parameter;Ich;Hybrid Rate Constants;ADME;Steady State Plasma Concentration;Non-compartmental Analysis;Maximum Plasma Concentration;Dosing Interval;Plasma Concentration Time Profile;Clavulanic Acid;Ideal Body Weight
