Biostatistics in Biopharmaceutical Research and Development

Biostatistics in Biopharmaceutical Research and Development

Clinical Trial Analysis, Volume 2

Chen, Ding-Geng

Springer International Publishing AG

01/2025

440

Dura

9783031659362

Pré-lançamento - envio 15 a 20 dias após a sua edição

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Statistical Challenges in the Analysis of Biomarker Data.- 2. Evaluating Predictive Accuracy of Prognostic Model for Censored Time-to-Event Data Analysis in Clinical Trials.- Statistical Methods for Accommodating Immortal Time: A Selective Review and Comparison.- Variable selection for partially functional additive Cox Model with interval-censored failure time data.- A Bayesian proportional hazards model to predict patient recruitment in multicenter clinical trials.- GET MORE INFORMATION FROM RECURRENT EVENTS DATA.- Introduction to Patient Preference Studies.- Machine Learning for Precision Medicine and Humanized AI for Future Healthcare.- The Statistical Evaluation of Surrogate Endpoints in Clinical Trials???????.- Treatment Effect Estimation Using Data from Observational and Non-Randomized Studies???????.- Methods for Comparing Two Treatments for a Dichotomous Outcome for a Two-Period Design with Treatment Switching of Control Group Period 1 Non-Responders.- Regression-based estimation of optimal adaptive treatment strategies: Key methods???????.- Vaccine Disease-Prevention Efficacy Studies: Traditional Approaches and New Frontiers???????.- Covariate Adjustment in Analyzing Randomized Clinical Trials: Approaches, Software, and Application???????.- Joint correlated responses and feedback effect with time-dependent covariates.- Distributions and Their Approximations for P-Values.
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Biopharmaceuticals;clinical trials;biostatistics;statistics;public health