Antibody-Drug Conjugates and Cellular Metabolic Dynamics

Antibody-Drug Conjugates Basic Concepts and Structures.- Relationship between target and specific action of antibody-drugs conjugates.- The internalization and therapeutic activity of antibody drug conjugate.- The internalization and intracellular trafficking of ADC.- Distribution and metabolism of antibody-drug conjugates.- Application of Antibody fragments in ADCs.- Novel Targeting Carriers in Antibody-drug Conjugates.- Site-specified Conjugating Technology and Application.- Determination of drug-to-antibody ratio of ADCs.- Pharmacokinetic study of antibody-drug conjugates.

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• Química
• Biologia, ciências da vida
• Equipamentos científicos, experiências e técnicas
• Medicina pré-clínica: ciências básicas
• Pesquisa médica
• Biologia Celular (citologia)

Antibody-drug conjugates;Cellular Metabolic Dynamics;Cellular internalization;Intracellular trafficking;Novel Targeting Carriers;Site-specified Conjugating Technology