Alzheimer's Disease Research
portes grátis
Alzheimer's Disease Research
What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift
Behl, Christian
Springer International Publishing AG
07/2023
652
Dura
Inglês
9783031315695
15 a 20 dias
Descrição não disponível.
Chapter 1. Introduction.- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings.- Chapter 3. Alzheimer's Disease Research After 1945: The Recommencement.- Chapter 4. Alzheimer's Research Goes Deeper - Ultrastructural Electron Microscopy Studies.- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer's Disease.- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer's Disease.- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer's Disease.- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor.- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer's Disease.- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals.- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas?.- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis.- Chapter 13. Focus on Tauopathies and Beyond.- Chapter 14. Alzheimer's Research Gains Momentum and Spreads Out.- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally.- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way.- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias?.- Chapter 19. Driving Forces of Alzheimer's Research Directions.- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last?.- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".
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Alzheimer;Amyloid;Alzheimer Clinics;Alzheimer Therapy;Alzheimer's Disease;Amyloid Plaques;Amyloid-Cascade-Hypothesis;Agenda Setting;Aternative Hypotheses;Dementia;Risk Factors;Tau
Chapter 1. Introduction.- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings.- Chapter 3. Alzheimer's Disease Research After 1945: The Recommencement.- Chapter 4. Alzheimer's Research Goes Deeper - Ultrastructural Electron Microscopy Studies.- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer's Disease.- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer's Disease.- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer's Disease.- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor.- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer's Disease.- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals.- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas?.- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis.- Chapter 13. Focus on Tauopathies and Beyond.- Chapter 14. Alzheimer's Research Gains Momentum and Spreads Out.- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally.- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way.- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias?.- Chapter 19. Driving Forces of Alzheimer's Research Directions.- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last?.- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".
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