Why the Dose Matters

Why the Dose Matters

Assessing the Health Risk of Exposure to Toxicants

Boelsterli, Urs A.

Taylor & Francis Ltd

08/2024

236

Mole

9781032387642

15 a 20 dias

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1. Introduction. Part I The Concepts: Hazard and Exposure 2. What Does "Toxic" Mean? 3. Paracelsus Reloaded-The Dose Concept. 4. Exposure-The Key Determinant in Risk Assessment. 5. Natural and Synthetic Chemicals. 6. What Our Body Does to a Chemical. 7. What a Chemical Does to Our Body. 8. Defense Shields. 9. Correlation and Causality. Part II The Chemicals 10. Pesticides-Killers with a License. 11. Toxic Food. 12. Dietary Supplements - The More The Better? 13. Significant Risks: Persistent and Widespread. 14. Drugs. Part III The Risk 15. Safety Assessment. 16. Acceptable Limits, Tolerance, and Red Lines. 17. Risk Assessment. 18. Gauging the Risk Against the Benefit. 19. Risk Communication. Part IV The Future 20. Toxicological Challenges. 21. Conclusions and Outlook.
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Toxicology;Environmental pollution;Drug Development;Pesticides;Foods;Chronic;Human Health Risk;Holds;Toxic Response;Lab Animals;Animal Study;Wo;Monoxide;Vice Versa;Data Poor Chemicals;Methyl Mercury;Acceptable Daily Intake;RfD;MEHP;Margin Of Exposure;Residual Pesticides;TCDD;Herbal Dietary Supplements;Reactive Metabolite;Cancer Slope Factors;Maximum Residue Limits;Adverse Drug Reactions;Foreign Chemicals;Dose Response Curve;Endocrine Disruptors