mRNA Metabolism in Human Disease

mRNA Metabolism in Human Disease

Romao, Luisa

Springer Nature Switzerland AG

08/2020

180

Mole

Inglês

9783030199685

15 a 20 dias

454

Descrição não disponível.
Prelims.- Networks of mRNA processing and alternative splicing regulation in health and disease.- The diverse roles of RNA-binding proteins in glioma development.- Nonsense-mediated mRNA decay in development, stress and cancer.- Implication of mRNA degradation disorders on human DISease: focus on DIS3 and DIS3-like enzymes.- Translational regulation by upstream open reading frames and human diseases.- Alternative mechanisms of mRNA translation initiation in cellular stress response and cancer.- RNA therapeutics: how far have we gone? Index.
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mRNA metabolism;gene expression regulation;human genetic disease;cancer;RNA-based therapeutics;Translatome