Dynamic Nature of Mitochondria

Dynamic Nature of Mitochondria

from Ultrastructure to Health and Disease

Reichert, Andreas S.

Taylor & Francis Ltd

04/2024

198

Dura

Inglês

9781032117133

15 a 20 dias

Descrição não disponível.
I. Mitochondrial ultrastructure - molecular mechanisms shaping the inner membrane. 1. Roles of the F1FO-ATP synthase and MICOS in mitochondrial membrane organization. 2. Proteolytic regulation of mitochondrial architecture. II. Mitochondrial cristae and lipid dynamics: from super-resolution microscopy to lipid-OXPHOS interplay. 3. Changes in cristae architecture and function: from static to dynamic. 4. Emerging roles of phospholipids in the structure and function of the Oxidative Phosphorylation complexes. III. Mitochondrial control of cellular homeostasis - from redox signaling to interorganellar contact-sites. 5. Mitochondrial Hydrogen Peroxide Dynamics. 6. Mitochondria-lysosome crosstalk, in disease and in health. IV. Mitochondria in health and disease: from mtDNA release to Complex I assembly. 7. mtDNA in & out - On the tightrope of cellular health. 8. Mitochondrial Complex I Assembly and Implications for Mitochondrial Disease. V. Advanced methods in mitochondrial biology and metabolism research. 9. The optogenetic landscape of the mitochondrion. VI. Integrative view on mitochondrial research and outlook. 10. Mitochondrial biology - a vibrating and dynamic research field still breaking boundaries.
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metabolism;dysfunction;aging;oxidative stress;organelles