Carbonic Anhydrases: Current and Emerging Therapeutic Targets

Dedication.- Preface.-The carbonic anhydrases in health and disease.- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets.- Targeting carbonic anhydrases in vascular and pulmonary disease.- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema.- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders.- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes.- An overview of carbonic anhydrase-related neoplasms.- The carbonic anhydrase IX interactome and the regulation of cancer progression.- Carbonic anhydrase IX: current and emerging therapies.- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents.- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening.- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.

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• Farmacologia
• Farmácia / receituário
• Pesquisa médica
• Bioquímica

Carbonic Andhydrase;Carbonic Anhydrase Inhibitors;Therapeutic Cancer Agent;Neurological Disorders;Ophthalmology;Diabetes