RAS: Past, Present, and Future
portes grátis
RAS: Past, Present, and Future
O'Bryan, John P.; Piazza, Gary
Elsevier Science Publishing Co Inc
02/2022
356
Dura
Inglês
9780128244852
15 a 20 dias
730
Descrição não disponível.
1. A brief history of RAS and the RAS Initiative
Frank McCormick
2. Not all RAS mutations are equal: A detailed review of the functional diversity of RAS hot spot mutations
Rachel A. Burge and G. Aaron Hobbs
3. Drug targeting opportunities en route to Ras nanoclusters
Karolina Pavic, Rohan Chippalkatti, and Daniel Abankwa
4. Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer
J. Nathaniel Diehl, Priya S. Hibshman, Irem Ozkan-Dagliyan, Craig M. Goodwin, Sarah V. Howard, Adrienne D. Cox, and Channing J. Der
5. Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone
Alexander B. Coley, Antonio Ward, Adam B. Keeton, Xi Chen, Yulia Maxuitenko, Aishwarya Prakash, Feng Li, Jeremy B. Foote, Donald J. Buchsbaum, and Gary A. Piazza
6. Targeting RAS oncogenesis with SOS1 inhibitors
Roman Christian Hillig and Benjamin Bader
7. Inhibition of SHP2 as an approach to block RAS-driven cancers
Yu-Ting Chou and Trever G. Bivona
8. Targeting the "undruggable? RAS with biologics
Michael Whaby, Imran Khan, and John P. O'Bryan
9. Unraveling and targeting RAS-driven metabolic signaling for therapeutic gain
Jonathan M. DeLiberty, Ryan Robb, Claire E. Gates, and Kirsten L. Bryant
10. The RASopathies: Biology, genetics and therapeutic options
Jody Fromm Longo and Steven L. Carroll
Frank McCormick
2. Not all RAS mutations are equal: A detailed review of the functional diversity of RAS hot spot mutations
Rachel A. Burge and G. Aaron Hobbs
3. Drug targeting opportunities en route to Ras nanoclusters
Karolina Pavic, Rohan Chippalkatti, and Daniel Abankwa
4. Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer
J. Nathaniel Diehl, Priya S. Hibshman, Irem Ozkan-Dagliyan, Craig M. Goodwin, Sarah V. Howard, Adrienne D. Cox, and Channing J. Der
5. Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone
Alexander B. Coley, Antonio Ward, Adam B. Keeton, Xi Chen, Yulia Maxuitenko, Aishwarya Prakash, Feng Li, Jeremy B. Foote, Donald J. Buchsbaum, and Gary A. Piazza
6. Targeting RAS oncogenesis with SOS1 inhibitors
Roman Christian Hillig and Benjamin Bader
7. Inhibition of SHP2 as an approach to block RAS-driven cancers
Yu-Ting Chou and Trever G. Bivona
8. Targeting the "undruggable? RAS with biologics
Michael Whaby, Imran Khan, and John P. O'Bryan
9. Unraveling and targeting RAS-driven metabolic signaling for therapeutic gain
Jonathan M. DeLiberty, Ryan Robb, Claire E. Gates, and Kirsten L. Bryant
10. The RASopathies: Biology, genetics and therapeutic options
Jody Fromm Longo and Steven L. Carroll
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
RAS; oncogenes; cancer biology; pharmacological inhibitors
1. A brief history of RAS and the RAS Initiative
Frank McCormick
2. Not all RAS mutations are equal: A detailed review of the functional diversity of RAS hot spot mutations
Rachel A. Burge and G. Aaron Hobbs
3. Drug targeting opportunities en route to Ras nanoclusters
Karolina Pavic, Rohan Chippalkatti, and Daniel Abankwa
4. Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer
J. Nathaniel Diehl, Priya S. Hibshman, Irem Ozkan-Dagliyan, Craig M. Goodwin, Sarah V. Howard, Adrienne D. Cox, and Channing J. Der
5. Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone
Alexander B. Coley, Antonio Ward, Adam B. Keeton, Xi Chen, Yulia Maxuitenko, Aishwarya Prakash, Feng Li, Jeremy B. Foote, Donald J. Buchsbaum, and Gary A. Piazza
6. Targeting RAS oncogenesis with SOS1 inhibitors
Roman Christian Hillig and Benjamin Bader
7. Inhibition of SHP2 as an approach to block RAS-driven cancers
Yu-Ting Chou and Trever G. Bivona
8. Targeting the "undruggable? RAS with biologics
Michael Whaby, Imran Khan, and John P. O'Bryan
9. Unraveling and targeting RAS-driven metabolic signaling for therapeutic gain
Jonathan M. DeLiberty, Ryan Robb, Claire E. Gates, and Kirsten L. Bryant
10. The RASopathies: Biology, genetics and therapeutic options
Jody Fromm Longo and Steven L. Carroll
Frank McCormick
2. Not all RAS mutations are equal: A detailed review of the functional diversity of RAS hot spot mutations
Rachel A. Burge and G. Aaron Hobbs
3. Drug targeting opportunities en route to Ras nanoclusters
Karolina Pavic, Rohan Chippalkatti, and Daniel Abankwa
4. Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer
J. Nathaniel Diehl, Priya S. Hibshman, Irem Ozkan-Dagliyan, Craig M. Goodwin, Sarah V. Howard, Adrienne D. Cox, and Channing J. Der
5. Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone
Alexander B. Coley, Antonio Ward, Adam B. Keeton, Xi Chen, Yulia Maxuitenko, Aishwarya Prakash, Feng Li, Jeremy B. Foote, Donald J. Buchsbaum, and Gary A. Piazza
6. Targeting RAS oncogenesis with SOS1 inhibitors
Roman Christian Hillig and Benjamin Bader
7. Inhibition of SHP2 as an approach to block RAS-driven cancers
Yu-Ting Chou and Trever G. Bivona
8. Targeting the "undruggable? RAS with biologics
Michael Whaby, Imran Khan, and John P. O'Bryan
9. Unraveling and targeting RAS-driven metabolic signaling for therapeutic gain
Jonathan M. DeLiberty, Ryan Robb, Claire E. Gates, and Kirsten L. Bryant
10. The RASopathies: Biology, genetics and therapeutic options
Jody Fromm Longo and Steven L. Carroll
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
