Proteostasis and Proteolysis

Proteostasis and Proteolysis

Pick, Elah; Gioran, Anna; Chondrogianni, Niki

Taylor & Francis Ltd

12/2021

251

Dura

Inglês

9780367499327

15 a 20 dias

734

Descrição não disponível.
Preface. Contributors. The Editors. Ribosomal Pauses during Translation and Proteostasis. Protein Folding and Misfolding: Deciphering Mechanisms of Age-Related Diseases. Transcriptional Regulation of Proteostatic Mechanisms. MicroRNAs as Central Regulators of Adult Myogenesis and Proteostasis Loss in Skeletal Muscle Aging. mRNA Granules and Proteostasis in Aging and Age-Related Diseases. Phospholipids and the Unfolded Protein Response. Ubiquitin Ligases Involved in Progeroid Syndromes and Age-Associated Pathologies. Role of SUMOylation in Neurodegenerative Diseases and Inflammation. NEDD8 and Oxidative Stress. Structure, Function and Regulators of the 20S Proteasome. Cellular Responses to Proteasome Impairment. Proteasome Fate in Aging and Proteinopathies. The Proteasomal System in Cancer. Proteostasis and Skin Aging. Reactive Oxygen Species and Protein Homeostasis in Skeletal Muscle Regeneration. Protein Degradation in Cardiac Health and Disease. Autophagy in Aging and Oxidative Stress. Autophagy in Aging and Longevity Exemplified by the Aging Heart. Index.
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ULK1 Complex;AMPK Signaling;Mitochondrial UPRs;Proteasome Peptidase Activities;CMA;Cullin Ring Ligase;Heat Shock;Ros Production;Proteasome Impairment;E3 Ligase;Muscle Ring Finger;Ring Type E3;26S Proteasome;Autophagic Flux;Mitogen Activated Protein Kinase;MAPK;ER Stress;PQC System;ER Lumen;Von Hippel Lindau Disease Tumor Suppressor;UPR Signaling;Sumo Conjugation;Sumo E3 Ligase;Satellite Cell Function;Satellite Cells