Protein Interactions as Targets in Drug Discovery

Protein Interactions as Targets in Drug Discovery

Donev, Rossen

Elsevier Science Publishing Co Inc

04/2020

316

Dura

Inglês

9780128168462

15 a 20 dias

630

Descrição não disponível.
1. Latest trends in structure based drug design with protein targets Angshuman Bagchi 2. From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD) Stefano Moro 3. Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis M. Michael Gromiha 4. Aromatic-aromatic interactions in protein-drug and protein-protein interactions Adrian Gustavo Turjanski 5. Role of protein-protein interaction in allosteric drug design within the human methyltransferome Guang Hu 6. Protein-Protein Interactions as the Basis for Cyclin-Dependent Kinase Inhibition Mark Klein 7. Targeting FOXP3 complex ensemble in drug discovery Bin Li 8. Targeting arrestin interactions with its partners for therapeutic purposes Vsevolod V. Gurevich 9. Protein interactomics in kidney stone research Visith Thongboonkerd 10. Human oral microbiome protein-protein interaction: a cross-talk with health systemic implications Marlene M.T. Barros 11. Protein-protein complexes as targets for drug discovery against infectious diseases Yusuf Akhter 12. Therapeutic intervention of protein-protein interactions in innate immunity Kevin J. Lumb 13. Physicochemical determinants of antibody-protein interactions Sibel Kalyoncu Uzunlar
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Allosteric pocket; Antibody; Antigen; Antimicrobial; Arrestin; Binding interaction; Biologics; Biopharmaceuticals; Cell cycle; Cyclin; Cyclin-dependent kinase; DNMTs; Docking; Drug deign; Drug discovery; Drug resistance; Drug targets; Epitope; FOXP3; Gene therapy; GPCR; Host-microbial interactomics; IL-17; IL-23; Immune therapy; In silico interactomics; Inhibitors; MDR/XDR; Molecular docking; Molecular dynamics simulations; Nanobody; Network theory; Oral microbial targets; Paratope; Physicochemical characteristics; Post-translational modification; PPIs in saliva; Protein-ligand interactions; Protein-protein complexes; Protein-protein interaction; Protein-protein interactions; Quantitative structure-activity relationship (QSAR); Receptor specificity; Saliva diagnostics; Signaling; Signaling bias; Small molecules; Structural biology; Structure based drug design; Structure based virtual screening; Thermodynamics of protein-ligand interactions; Transcription; Treg; Virtual screening fragment;