Orthobiologics
portes grátis
Orthobiologics
Injectable Therapies for the Musculoskeletal System
Filardo, Giuseppe; Rodeo, Scott A.; Mandelbaum, Bert R.; Muschler, George F.; Nakamura, Norimasa
Springer Nature Switzerland AG
12/2021
402
Dura
Inglês
9783030847432
15 a 20 dias
1101
Descrição não disponível.
I. Injectable OrthoBiologics: Formulations and Rationale 1. Bone marrow-derived cultured stromal cells and Bone Marrow Concentrate.- 2. Adipose-derived cultured stromal cells and Stromal Vascular Fraction from adipose tissue.- 3. Synovial-derived cultured stromal cells.- 4. Amniotic, Placenta, and Umbilical cord-derived cultured stromal cells.- 5. Allogeneic cells: pros and cons.- 6. Steroid hormones.- 7. Cytokines, chemokines, alpha-2-macroglobulin, growth factors.- 8. Platelet-rich plasma: leucocyte-rich, leukocyte-poor, autologous conditioned serum, autologous protein solution.- 9. Amniotic tissue extract, placenta tissue extract.- 10. Extracellular vesicles (exosomes).- II. Injectable OrthoBiolologics: evaluation methods and results based on pathology and anatomy.- 11. Rotator cuff tendinopathy: cell therapy.- 12. Rotator cuff tendinopathy: biologics.- 13. Tennis elbow: cell therapy.- 14. Tennis elbow: cell therapy biologics.- 15. Patellar tendinopathy: cell therapy.- 16. Patellar tendinopathy: biologics.- 17. Achilles tendinopathy: cell therapy.- 18. Achilles tendinopathy: biologics.- 19. Plantar Fasciitis: cell therapy.- 20. Plantar Fasciitis: biologics.- 21. Ligament lesions: cell therapy.- 22. Ligament lesions: biologics.- 23. Meniscal lesions: cell therapy.- 24. Meniscal lesions: biologics.- 25. Muscle lesions: cell therapy.- 26. Muscle lesions: biologics.- 27. Fractures (incl. Nonunions): cell therapy.- 28. Fractures (incl. Nonunions): biologics.- 29. Cartilage lesions and Osteoarthritis of the knee: cell therapy.- 30. Cartilage lesions and Osteoarthritis of the knee: biologics.- 31. Cartilage lesions and Osteoarthritis of the hip and ankle: cell therapy.- 32. Cartilage lesions and Osteoarthritis of the hip and ankle: biologics.- III. Future directions 33. Pluripotent stem cells: Embryonic/Fetal stem cells and induced pluripotent stem (iPS) cells.- 34. Gene therapy.- 35.Stimulation of the intrinsic stromal cell niche.- 36 Conclusions.
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cell therapy;biologics;tendinopathy;fractures;ostheoarthritis;stem cells;cartilage lesions;gene therapy;rotator cuff;muscle lesions;bone non-union
I. Injectable OrthoBiologics: Formulations and Rationale 1. Bone marrow-derived cultured stromal cells and Bone Marrow Concentrate.- 2. Adipose-derived cultured stromal cells and Stromal Vascular Fraction from adipose tissue.- 3. Synovial-derived cultured stromal cells.- 4. Amniotic, Placenta, and Umbilical cord-derived cultured stromal cells.- 5. Allogeneic cells: pros and cons.- 6. Steroid hormones.- 7. Cytokines, chemokines, alpha-2-macroglobulin, growth factors.- 8. Platelet-rich plasma: leucocyte-rich, leukocyte-poor, autologous conditioned serum, autologous protein solution.- 9. Amniotic tissue extract, placenta tissue extract.- 10. Extracellular vesicles (exosomes).- II. Injectable OrthoBiolologics: evaluation methods and results based on pathology and anatomy.- 11. Rotator cuff tendinopathy: cell therapy.- 12. Rotator cuff tendinopathy: biologics.- 13. Tennis elbow: cell therapy.- 14. Tennis elbow: cell therapy biologics.- 15. Patellar tendinopathy: cell therapy.- 16. Patellar tendinopathy: biologics.- 17. Achilles tendinopathy: cell therapy.- 18. Achilles tendinopathy: biologics.- 19. Plantar Fasciitis: cell therapy.- 20. Plantar Fasciitis: biologics.- 21. Ligament lesions: cell therapy.- 22. Ligament lesions: biologics.- 23. Meniscal lesions: cell therapy.- 24. Meniscal lesions: biologics.- 25. Muscle lesions: cell therapy.- 26. Muscle lesions: biologics.- 27. Fractures (incl. Nonunions): cell therapy.- 28. Fractures (incl. Nonunions): biologics.- 29. Cartilage lesions and Osteoarthritis of the knee: cell therapy.- 30. Cartilage lesions and Osteoarthritis of the knee: biologics.- 31. Cartilage lesions and Osteoarthritis of the hip and ankle: cell therapy.- 32. Cartilage lesions and Osteoarthritis of the hip and ankle: biologics.- III. Future directions 33. Pluripotent stem cells: Embryonic/Fetal stem cells and induced pluripotent stem (iPS) cells.- 34. Gene therapy.- 35.Stimulation of the intrinsic stromal cell niche.- 36 Conclusions.
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