Opioids

Part I. Social aspects of opioid use.- Chapter 1: A brief history of opioids and the evolution of concepts associated with substance use disorders.- Chapter 2: The two sides of opioid use: Unmet needs of opioids for pain management and the role of opioids in substance use disorders.- Chapter 3: Opioid markets and special populations.- Chapter 4: Towards a new drug policy agreement.- Chapter 5: The opioid crises.- Chapter 6: Persons who misuse opioids.- Chapter 7: The need for structural interventions for persons who misuse opioids.- Part II. Pharmacological and medical aspects of opioid use.- Chapter 8: Opioid effects and classification.- Chapter 9: Opioid receptors and neuronal signal transduction.- Chapter 10: Opioids in Pain.- Chapter 11: Opioids in Palliative Care.- Chapter 12: Opioids and the immune system.- Chapter 13: Opioid dependence, tolerance, and withdrawal.- Chapter 14: Medication-Assisted Treatment (MAT) 1: Opioid substitution therapy.- Chapter 15: Medication-Assisted Treatment for Opioid Use Disorders 2. Detoxification.- Chapter 16: Synthetic Opioids as New Psychoactive Substances (NPS).

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• Farmacologia
• Neurociências
• Neurologia e neurofisiologia clínica
• Dôr e gestão da dôr

Opioids;heroin;fentanyl;opioid peptide;opiod receptors subtypes;TLR4 receptors;neuroinflammation;innate immunity;adaptive immunity;functional selectivity;biased agonism;opioid crisis;pain management;opioid use disorders;opioid dependence;drug-assisted therapy