Omics Approaches to Understanding Muscle Biology

Omics Approaches to Understanding Muscle Biology

Chen, Yi-Wen; Burniston, Jatin George

Springer-Verlag New York Inc.

11/2020

217

Mole

Inglês

9781493998043

15 a 20 dias

454

Descrição não disponível.
Part I: Genomic and Epi-genomic.- 1) GWAS/muscle function and diseases (by Eric Hoffman).- 2) Whole genome and whole exon sequencing/muscle disorders (by Silvere van der Maarel and Richard Lemmers).- 3) Epi-genome approaches/muscle regeneration (by Vittorio Sartorelli).- Part II: Transcriptomic.- 4) RNA profiling (by Yi-Wen Chen, confirmed).- 5) miRNA profiling (by Alyson Fiorillo).- 6) Single cell profiling in muscle (byPier Lorenzo Puri).- 7) Statistics and bioinformatics (by Heather Gordish).- Part III: Proteomic.- 8). Proteome profiling of human/ clinical samples - i.e. necessarily label-free techniques (by Lawrence Mandarino).- 9) Proteome profiling of cell and animal models - i.e. label techniques such as SILAC (by Matthias Mann OR SILAM with JR Yates III).- 10) Global analysis of post-translational modifications (by David E James).- 11) Proteome dynamics - synthesis and degradation on a proteome wide scale (by Jatin Burniston, confirmed).- Part IV: Metabolomic.- 12) Non-targeted metabolomics using mass spectrometry (by Charles Burant).
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Skeletal muscle;Skeletal muscle physiology;skeletal muscle development;OMICS technologies;muscular dystrophy;high-throughput analytical techniques;RNA profiling;muscle atrophy and dysfunction;Proteomics;Metabolomics;Systems Biology