Nuclear Receptors
portes grátis
Nuclear Receptors
The Art and Science of Modulator Design and Discovery
Badr, Mostafa Z.
Springer Nature Switzerland AG
09/2022
679
Mole
Inglês
9783030784386
15 a 20 dias
Descrição não disponível.
1. Molecular Pharmacology of the Youngest Member of the Nuclear Receptor Family: The Mineralocorticoid Receptor.- 2. A Simple Method for Visual Assessment and Quantification of Altered Subcellular Localization of Nuclear Receptors.- 3. Multifaceted Effects of Ligand on Nuclear Receptor Mobility.- 4. Chemical Considerations in Discovery of Receptor Modulators.- 5. Structure-Based Design of Estrogen-Related Receptors Modulators.- 6. PPAR? and ? ligand design - Honing the traditional empirical method with a more holistic overview.- 7. Pregnane X Receptor: understanding its function and activity at the molecular level.- 8. Ligand Design for the Vitamin D Receptor.- 9. What Makes a Good Antagonist: Lessons Learned from the Estrogen and Aryl Hydrocarbon Receptors.- 10. Design of Novel PPAR agonist for Neurodegenerative Disease.- 11. Functional bioassays lithograph ligand reflections in the PPARalpha sphere.- 12. Computational applications on Food Contact Chemicals as Nuclear Receptors binders.- 13. Alternation of Nuclear Hormone Receptor Signaling by Antiviral Drugs.- 14. Retinoic acid-related orphan receptor (ROR) inverse agonists: potential therapeutic strategies for multiple inflammatory diseases.- 15. Therapeutic Strategies to Target Activating Estrogen Receptor a Mutation.- 16. Androgen Receptors in the Pathology of Disease.- 17. Bilirubin: A Ligand of the PPAR? Nuclear Receptor.- 18. Nuclear Receptor Ligands in Flavivirus Infection Control.- 19. Use of Nanotechnology to Improve 15d-PGJ2 Immunomodulatory Activities.- 20.Ligand-independent Activation of PPARs.- 21. PPAR Modulation Through Posttranslational Modification Control.- 22. Developing Inhibitors to the Amino-Terminus Domains of Steroid Hormone Receptors.- 23. Redirecting the cellular waste disposal machinery to target transcription.
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molecular pharmacology;drug design;PPAR;PXR;metabolic diseases;vitamin d receptor;ligand;target transcription;RXR Phosphorylation;RXRalpha;neuropathy;therapeutic strategies;phytochemicals;androgen receptors;inflammatory disease;infectious diseases;ROR inverse agonists
1. Molecular Pharmacology of the Youngest Member of the Nuclear Receptor Family: The Mineralocorticoid Receptor.- 2. A Simple Method for Visual Assessment and Quantification of Altered Subcellular Localization of Nuclear Receptors.- 3. Multifaceted Effects of Ligand on Nuclear Receptor Mobility.- 4. Chemical Considerations in Discovery of Receptor Modulators.- 5. Structure-Based Design of Estrogen-Related Receptors Modulators.- 6. PPAR? and ? ligand design - Honing the traditional empirical method with a more holistic overview.- 7. Pregnane X Receptor: understanding its function and activity at the molecular level.- 8. Ligand Design for the Vitamin D Receptor.- 9. What Makes a Good Antagonist: Lessons Learned from the Estrogen and Aryl Hydrocarbon Receptors.- 10. Design of Novel PPAR agonist for Neurodegenerative Disease.- 11. Functional bioassays lithograph ligand reflections in the PPARalpha sphere.- 12. Computational applications on Food Contact Chemicals as Nuclear Receptors binders.- 13. Alternation of Nuclear Hormone Receptor Signaling by Antiviral Drugs.- 14. Retinoic acid-related orphan receptor (ROR) inverse agonists: potential therapeutic strategies for multiple inflammatory diseases.- 15. Therapeutic Strategies to Target Activating Estrogen Receptor a Mutation.- 16. Androgen Receptors in the Pathology of Disease.- 17. Bilirubin: A Ligand of the PPAR? Nuclear Receptor.- 18. Nuclear Receptor Ligands in Flavivirus Infection Control.- 19. Use of Nanotechnology to Improve 15d-PGJ2 Immunomodulatory Activities.- 20.Ligand-independent Activation of PPARs.- 21. PPAR Modulation Through Posttranslational Modification Control.- 22. Developing Inhibitors to the Amino-Terminus Domains of Steroid Hormone Receptors.- 23. Redirecting the cellular waste disposal machinery to target transcription.
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
