Neurodevelopmental Disorders

Neurodevelopmental Disorders

Employing iPSC Technologies to Define and Treat Childhood Brain Diseases

DiCicco-Bloom, Emanuel; Millonig, James H.

Springer Nature Switzerland AG

06/2021

305

Mole

Inglês

9783030454951

15 a 20 dias

486

Descrição não disponível.
1. Modeling neurodevelopmental deficits in Tuberous Sclerosis Complex with stem cell-derived neural precursors and neurons.- 2. Advances in human stem cells and genome editing to understand and develop treatment for Fragile X syndrome.- 3. IPSC MODELS OF CHROMOSOME 15Q IMPRINTING DISORDERS: FROM DISEASE MODELING TO THERAPEUTIC STRATEGIES.- 4. Creating iPSC based models to understand the signaling and cellular phenotypes in idiopathic autism and 16p11.2 derived neurons.- 5. Dysregulation of Neurite Outgrowth and Cell Migration in Autism and other Neurodevelopmental Disorders.- 6. Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells.- 7. Modeling Inflammation on Neurodevelopmental disorders using pluripotent stem cells.- 8. Astrocyte-derived exosomes in an iPSC model of bipolar disorder.- 9. Two- and there-dimensional stem cell models to define mechanisms underlying psychiatric disorders.- 10. Development of a 3-D organoid system using human induced pluripotent stem cells to model idiopathic autism.
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iPSCs;Autism;Schizophrenia;Syndromic Autism;Bipolar Disorder;Neurodevelopmental Gene Risk Factors