Models, Molecules and Mechanisms in Biogerontology

I. Alterations in Cellular Mechanisms during Aging
1. Protein Structure and Function in Aging and Age-Related Diseases
2. DNA, DNA Replication and Aging

3. Transcription and Aging
4. Ribosomes, Translation and Aging
5. p53 and Aging
6. Paired box (Pax) Transcription Factors and Aging
7. Telomeres, Telomerase and Aging
8. The Epigenome of Ageing
9. Attaining Epigenetic Rejuvenation: Challenges Ahead
10. Mitochondria as a Key Player in Aging
11. Aging, Free Radicals and Reactive Oxygen Species: an Evolving Concept
12. Stem cells and Aging
13. Can autophagy stop the clock: Unravelling the mystery in Dictyostelium discoideum
14. Aging: Reading, Reasoning and Resolving using Drosophila as a Model System
15. Nothobranchius furzeri as a new model system for aging studies
II. Alterations in Metabolism during Aging and Diseases
16. Aging in muscle
17. Metabolic Diseases and Aging
18. Interplay between Nutrient Sensing Molecules during Aging and Longevity

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• Biologia Celular (citologia)
• Medicina geriátrica
• Engenharia biomédica
• Genética médica

GERONTOLOGY;NEURO-DEGENERATION;AGING;EPIGENETICS;GERIATRICS;MITOCHONDRIA;METABOLIC REGULATION;Metabolomics