MCB: CAR T Cells: Development, Characterization and Applications
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portes grátis
MCB: CAR T Cells: Development, Characterization and Applications
Galluzzi, Lorenzo; Spada, Sheila
Elsevier Science & Technology
02/2022
242
Dura
Inglês
9780323855013
15 a 20 dias
660
Descrição não disponível.
1. High-efficiency of genetic modification using CRISPR/Cpf1 system for engineered CAR T-cell therapy Renpeng Ding, Cheng-Chi Chao and Qianqian Gao 2. Determination of the biodistribution of chimeric antigen receptor-modified T cells against CD19 in NSG mice Hairuo Wen, Ying Huang, Tiantian Hou, Junzhi Wang and Yan Huo 3. Generation of CAR-T cells using lentiviral vectors Mansour Poorebrahim, Isaac Quiros-Fernandez, Elham Fakhr and Angel Cid-Arregui 4. Phenotyping of CAR T cells Sanjay Rathod 5. Evaluation of CAR-T cell cytotoxicity: Real-time impedance-based analysis Amanda N. Lisby, Robert D. Carlson, Trevor R. Baybutt, Megan Weindorfer and Adam E. Snook 6. Flow cytometry detection and quantification of CAR T cells into solid tumors Nicholas J.A. Tokarew, Javier Suarez Gosalvez, Alessia Nottebrock, Daria Briukhovestka, Stefan Endres, Bruno L. Cadilha and Sebastian Kobold 7. Generation and functional characterization of CAR exosomes Chuqi Wang, Wenyan Fu, Changhai Lei and Shi Hu 8. Preclinical testing of CAR T cells in zebrafish xenografts Sarah Grissenberger, Benjamin Salzer, Susana Pascoal, Andrea Wenninger-Weinzierl, Manfred Lehner and Martin Distel 9. In vivo experimental mouse model to test CD19 CAR T cells generated with different methods Anne Fane, Marit Renee Myhre, Else Marit Inderberg and Sebastien Waelchli 10. Non-invasive fluorescence imaging for tracking immune cells in preclinical models of immunotherapy Marcelo de Souza Fernandes Pereira, Aarohi Thakkar and Dean Anthony Lee 11. Generation of CAR T-cells using ?-retroviral vector Norihiro Watanabe and Mary Kathryn McKenna 12. Methods to monitor in vivo expansion and efficacy of CAR-T cells in preclinical models Mohammad Alhomoud, Jeremie Martinet, Mayumi Sugita, Alexandra Gomez-Arteaga and Monica L. Guzman 13. Strategies for manufacturing cell therapy products aligned with patient needs Prajna Guha and Steven C. Katz
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Activation; Adaptive immunotherapy; Adoptive T cell transfer; Adoptive transfer; Biodistribution; Bioluminescence; Bioreactors; Cancer; Cancer immunotherapy; CAR; CAR T cells; CAR-T; CAR-T cell; CAR-T cells; CAR-T manufacturing process; CAR-T monitoring; CAR-T PCR; CAR-T phenotypic analysis; CD19; Cell avidity analysis; Cell expansion; Central memory T cell; Chimeric antigen receptor; Chimeric antigen receptor (CAR); Chimeric antigen receptor T cells (CAR-T); Chimeric antigen receptors; CRISPR/Cpf1; Current good manufacturing practices (cGMP); Cytotoxic T cells; Cytotoxicity; DiR; Effector memory T cell; Effector T cell; Electroporation; Exosomes; Flow cytometry; Fluorescence imaging; Gammaretroviral vectors; Gene editing; Gene modification; Histopathology/immunochemistry; Immunophenotypic analysis; Immunotherapy; In vivo study; IVIS; Jurkat; Knock-in; Lentiviral vector; Leukapheresis; Leukemia; Memory stem T cells; Naive T cell; NK cells; NSG mice; On-target-off-tumor toxicity (OTOTT); Optical imaging; PBMC; Preclinical model; Preclinical testing; Protocol; Quality control; Real-time quantitative PCR; Systemic model; T cell; T cell tracking; T cell transduction; T cells subsets; Targeted therapy; Teal-time cell analysis (RTCA); Transposon system; xCELLigence; Xenograft model; Xenotransplantation; Zebrafish
1. High-efficiency of genetic modification using CRISPR/Cpf1 system for engineered CAR T-cell therapy Renpeng Ding, Cheng-Chi Chao and Qianqian Gao 2. Determination of the biodistribution of chimeric antigen receptor-modified T cells against CD19 in NSG mice Hairuo Wen, Ying Huang, Tiantian Hou, Junzhi Wang and Yan Huo 3. Generation of CAR-T cells using lentiviral vectors Mansour Poorebrahim, Isaac Quiros-Fernandez, Elham Fakhr and Angel Cid-Arregui 4. Phenotyping of CAR T cells Sanjay Rathod 5. Evaluation of CAR-T cell cytotoxicity: Real-time impedance-based analysis Amanda N. Lisby, Robert D. Carlson, Trevor R. Baybutt, Megan Weindorfer and Adam E. Snook 6. Flow cytometry detection and quantification of CAR T cells into solid tumors Nicholas J.A. Tokarew, Javier Suarez Gosalvez, Alessia Nottebrock, Daria Briukhovestka, Stefan Endres, Bruno L. Cadilha and Sebastian Kobold 7. Generation and functional characterization of CAR exosomes Chuqi Wang, Wenyan Fu, Changhai Lei and Shi Hu 8. Preclinical testing of CAR T cells in zebrafish xenografts Sarah Grissenberger, Benjamin Salzer, Susana Pascoal, Andrea Wenninger-Weinzierl, Manfred Lehner and Martin Distel 9. In vivo experimental mouse model to test CD19 CAR T cells generated with different methods Anne Fane, Marit Renee Myhre, Else Marit Inderberg and Sebastien Waelchli 10. Non-invasive fluorescence imaging for tracking immune cells in preclinical models of immunotherapy Marcelo de Souza Fernandes Pereira, Aarohi Thakkar and Dean Anthony Lee 11. Generation of CAR T-cells using ?-retroviral vector Norihiro Watanabe and Mary Kathryn McKenna 12. Methods to monitor in vivo expansion and efficacy of CAR-T cells in preclinical models Mohammad Alhomoud, Jeremie Martinet, Mayumi Sugita, Alexandra Gomez-Arteaga and Monica L. Guzman 13. Strategies for manufacturing cell therapy products aligned with patient needs Prajna Guha and Steven C. Katz
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
Activation; Adaptive immunotherapy; Adoptive T cell transfer; Adoptive transfer; Biodistribution; Bioluminescence; Bioreactors; Cancer; Cancer immunotherapy; CAR; CAR T cells; CAR-T; CAR-T cell; CAR-T cells; CAR-T manufacturing process; CAR-T monitoring; CAR-T PCR; CAR-T phenotypic analysis; CD19; Cell avidity analysis; Cell expansion; Central memory T cell; Chimeric antigen receptor; Chimeric antigen receptor (CAR); Chimeric antigen receptor T cells (CAR-T); Chimeric antigen receptors; CRISPR/Cpf1; Current good manufacturing practices (cGMP); Cytotoxic T cells; Cytotoxicity; DiR; Effector memory T cell; Effector T cell; Electroporation; Exosomes; Flow cytometry; Fluorescence imaging; Gammaretroviral vectors; Gene editing; Gene modification; Histopathology/immunochemistry; Immunophenotypic analysis; Immunotherapy; In vivo study; IVIS; Jurkat; Knock-in; Lentiviral vector; Leukapheresis; Leukemia; Memory stem T cells; Naive T cell; NK cells; NSG mice; On-target-off-tumor toxicity (OTOTT); Optical imaging; PBMC; Preclinical model; Preclinical testing; Protocol; Quality control; Real-time quantitative PCR; Systemic model; T cell; T cell tracking; T cell transduction; T cells subsets; Targeted therapy; Teal-time cell analysis (RTCA); Transposon system; xCELLigence; Xenograft model; Xenotransplantation; Zebrafish
