Ion and Molecule Transport in Lysosomes

Electrophysiological recording of endolysosomal channels. Endolysosmal two-pore channels and their regulation by mechanistic target of rapamycin (mTOR). Chloride transport across the lysosomal membrane. Mucolipin channels in lysosome storage disease. Ion channels of melanosomes and melanin formation. NAADP-mediated lysosomal Ca2+ release and NAADP receptors. Endolysosomal channels critical for endolysotosis and recycling. Mechanism of Ebola virus invasion via endocytic pathway and lysosome escape. The lysosomal H+ ATPase. Amino acid transport across the lysosomal membrane. Amino acid sensing at the lysosomal membrane. Cholesterol transport across the lysosomal membrane. Lysosomal peptide translocation. Chaperonemediated autophagy. Lysosomal membrane permeabilization.

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• Biologia molecular