Frontotemporal Dementias

Frontotemporal Dementias

Emerging Milestones of the 21st Century

Rademakers, Rosa; Boeve, Bradley; Buratti, Emanuele; Ghetti, Bernardino

Springer Nature Switzerland AG

01/2022

320

Mole

Inglês

9783030511425

15 a 20 dias

633

Descrição não disponível.
1. Behavioural variant FTD: recent advances in the diagnosis and understanding of the disorder.- 2. The neuropsychiatry of frontotemporal dementia.- 3. Nosology and Neuropathology of Language in Primary Progressive Aphasia.- 4. Measuring Behavior and Cognition in FTLD.- 5. Clinical update on C9orf72: FTD, ALS and beyond.- 6. Clinical aspects of familial FTLD associated with MAPT and GRN mutations.- 7. Neuroimaging in Frontotemporal Lobar Degeneration.- 8. The FTD Prevention Initiative - linking together genetic FTD cohort studies.- 9. Fluid Biomarkers of Frontotemporal Lobar Degeneration.- 10. Cross-cultural perspectives on frontotemporal degeneration.- 11. Clinical characteristics and Neuropathology of PSP, CBD and Related 4R-Tauopathies.- 12. Tau protein and frontotemporal dementias.- 13. FTLD-TDP pathological subtypes: clinical and mechanistic significance.- 14. Lysosomal dysfunction as a pathogenic mechanism in FTD: Evidence from PGRN and TMEM106B genetics and biology.- 15. Future trends in understanding the pathological role of TDP-43 and FUS proteins.- 16. Description of a new data resource for FTD including multiomic data on human post mortem brain (MAPT, GRN, C9orf72), matching mouse models and iPS models.- 17. Mendelian and sporadic FTD: avenues from genetics to disease pathways through in-silico prediction and modeling.- 18. FTLD treatment: Current Practice and Future Possibilities.
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Neurodeneration;Frontotemporal dementias;Clinical phenotypes;Neuropathology;Genetics;Molecular pathogenesis