Epitranscriptomics

Epitranscriptomics

Barciszewski, Jan; Jurga, Stefan

Springer Nature Switzerland AG

07/2021

632

Dura

Inglês

9783030716110

15 a 20 dias

1124

Descrição não disponível.
Epitranscriptomic Modifications and How to Find them.- Epitranscriptomic Signature in Neural Development and Disease.- The Emerging Neuroepitranscriptome.- Epitranscriptomics and Diseases.- Epitranscriptomic Marks and Systems Involved in Gene Regulation, Development and Disease.- Experimental Approaches and Computational Workflows for Systematic Mapping and Functional Interpretation of RNA Modifications.- RNA Modifications: The Mediator Between Cellular Stresses and Biological Effects.- Computational Prediction and Experimental Validation of Specific Modified RNA Sites.- Regulation of RNA Stability Utilizing RNA Modification.- Dynamic RNA Modification Upon Extracellular Stimulus.- RNA Methylation in Cancer.- Regulation of RNA Methylation yy TET Enzymes.- RNA N6-Methyladenosine and G-Quadruplex Structures in Bacteria.- RNA N6-Methyladenosine Chemical Modification as a Therapeutic Target.- Cap-Adjacent m6Am and its Effects On mRNA.- N6-Methyladenosine in The Heart.- The m6a RNA Methylation Regulates Oncogenic Signaling Pathways Driving Cell Transformation and Carcinogenesis.- Psivar: A Database of Functional Variants Involved in Pseudouridylation (?) with Implications for Disease Pathogenesis.- C-to-U RNA Editing by Mammalian APOBEC Enzymes.- The Powerful Mechanism of RNA Editing and its Therapeutic Potentials.- Noncanonical Caps in RNA.- Mass Spectrometry-Based Methods for Characterization of Hypomodifications in tRNA.- Dynamic mRNA Modifications in Plants.- The Mammalian Mitochondrial Epitranscriptome.- Epitranscriptomics Modifications of Micrornas: Classes, Detection, Impact on their Functionality and Next Frontiers.- "Look Before You Leap" when Editing the Introns, or the Secrets Behind the Intronic Post-Transcriptional Modification.- Functional Links Between the Internal N6-Methyl Adenosine Modifications in mRNAs and Human Diseases.- RNA Modifications in Neurodevelopment and Neurodegenerations.- Conventional and Advanced Techniques for Methyl-6-Adenosine Modification Mapping in Transcripts.- Mechanisms and Therapeutic Applications of RNA-Guided RNA Pseudouridylation.- Epitranscriptomic Modifications in lnRNA and miRNA in Cancer and Other Diseases.- RNA m6A and Adipogenesis.
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Epitranscriptome;RNA methylation;RNA modifications;RNA epigenetics;Neuroepitranscriptome;RNA editing;Posttranscriptional modification;Cancer;RNA viruses