Environmental Damage to DNA and the Protective Effects of Phytochemicals

Environmental Damage to DNA and the Protective Effects of Phytochemicals

Singh, Nitika; Sharma, Bechan

Taylor & Francis Ltd

08/2021

122

Dura

Inglês

9780367358228

15 a 20 dias

267

Descrição não disponível.
1 Introduction to the environmental factors and DNA damage 1

2 Molecular mechanisms of physical environmental factors as DNA-damage agents with special reference to (A) Radiations and (B) Temperature 13

3 Effects of chemical environmental factors (both natural and anthropogenic) on DNA and their modes of action. A. Organic factors (pesticides, dyes) B. Inorganic Factors (Heavy metals) 25

4 Biological factors causing DNA damage. A. Plant-based molecules. B. Animal-based molecules

5 Synergistic effects of environmental factors on DNA damage. A. Introduction to Synergism B. Synergistic effects C. Mechanism of actions

6 Introduction to phytochemicals and their actions on DNA. A. DNA-damaging action. B. DNA-protective function

7 Phytochemicals as DNA protectants and genotoxicants A. Phytochemicals as genotoxicants. B. Plant extract as DNA protectants. C. Isolated compounds as DNA protectants

8 Role of phytochemicals in protection of DNA from damage by different environmental factors. A. Physical factors (Thermal and radiation). B. Chemical factors (Organic and inorganic). C. Biological factors (Plants and animals)

9 DNA protective and genotoxic potential of environmental factors: Experimental models for the study

10 DNA damage: Overview, conclusion, and future perspective
DNA Damage;DNA Strand Break;Oxidative DNA Damage;DNA Damaging Potential;Induce DNA Damage;Alkaline Comet Assay;DNA Strand;DNA Protein Cross-linkage;DNA Protectant;DNA Base;DNA Adduct;Free Radical Induce DNA Damage;Plasmid pBR322 DNA;DNA Repair;Oxidative Chemical Species;DNA Repair Machinery;Assess DNA Damage;Comet Assay;DNA Methylation;DDR Signal;DNA Impairment;Argemone Oil;DNA Damage Detection;DNA Damage Agent;Bulky DNA Adduct