DNA Methyltransferases - Role and Function

Chapter 1. Mechanisms and biological roles of DNA methyltransferases and DNA methylation - from past achievements to future challenges.- Chapter 2.Bacterial DNA Methylation and Methylomes.- Chapter 3. ChapterDomain Structure of the Dnmt1, Dnmt3a, and Dnmt3b DNA Methyltransferases.- Chapter 4. Enzymology of Mammalian DNA Methyltransferases.- Chapter 5. Genetic Studies on Mammalian DNA Methyltransferase.- Chapter 6. Structure and Mechanism of Plant DNA Methyltransferases.- Chapter 7. DNA Methylation in Honey Bees and the Unresolved Questions in Insect Methylomics.- Chapter 8. N6-Methyladenine: A Conserved and Dynamic DNA Mark.- Chapter 9. Pathways of DNA Demethylation.- Chapter 10. Structure and Function of TET Enzymes.- Chapter 11.Proteins That Read DNA Methylation.- Chapter 12. Recent advances on DNA base flipping - a general mechanism for writing, reading, and erasing DNA modifications.-Chapter 13. The Role of DNA Methylation in Cancer.- Chapter 14. DNMTs and DNA damage.- Chapter 15. Role of DNMTs in brain.- Chapter 16. Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns.-Chapter 17. Inhibitors of DNA methylation.- Chapter 18. Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach? .- Chapter 19. DNA Labeling Using DNA Methyltransferases.

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• Biologia Celular (citologia)
• DNA e Genoma
• Biologia molecular
• Genética médica
• Enzimologia

DNA methylation;Epigenetics;Methyltransferase;Demethylation;DNA labelling;Cancer;Therapeutic targets;control of gene expression;Chromatin;Genome imprinting;Epigenetic editing;Cellular memory;Biomarkers;Reader proteins;Emerging technologies;DNA base flipping;DNA methylation signature;Dnmt1;Dnmt3a;Dnmt3b