DNA-Encoded Libraries

DNA-Encoded Libraries

Young, Damian W.; Brunschweiger, Andreas

Springer International Publishing AG

11/2022

276

Dura

Inglês

9783031186288

15 a 20 dias

600

Descrição não disponível.
A History of Selection-Based High-Throughput Screening Technologies for Hit Identification.- Barcoding Strategies for the Synthesis of Genetically Encoded Chemical
Libraries.- Advancements in DEL-Compatible Chemical Reactions.- Design Considerations in Constructing and Screening DNA-Encoded Libraries.- Cheminformatics Approaches Aiding the Design and Selection of DNA-Encoded Libraries.- Selection Strategies in DNA-Encoded Libraries.- From DEL Selections to Validated Hits to Clinical Leads.- A Perspective on 30 Years of DNA-Encoded Chemistry.


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Encoding Strategies;DNA-encoded Libraries;Target validation;Hit Identification;DNA fragments