Current Advances in the Science of Osteosarcoma

Current Advances in the Science of Osteosarcoma

Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models

Kleinerman, Eugenie S.; Gorlick, Richard

Springer Nature Switzerland AG

08/2020

233

Dura

Inglês

9783030430849

15 a 20 dias

671

Descrição não disponível.
The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies.- Genomics and the Immune Landscape of Osteosarcoma.- RECQ DNA Helicases and Osteosarcoma.- Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma.- Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma.- Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response.- Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma.- Wnt Signaling in Osteosarcoma.- Receptor Tyrosine Kinases in Osteosarcoma: 2019 update.- The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets.- Autophagy in OS.- Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs.- Exosomes: Dynamic Mediators of Extracellular Communication in the TumorMicroenvironment.- Comparative Immunology and Immunotherapy of Canine Osteosarcoma.- Index.
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bone cancer;cancer;metastasis;osteosarcoma;pediatric cancer