CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

1. The CRISPR/Cas9 Genome-editing System: Principles and Applications 2. Recent Applications of CRISPR-Cas9 in Genome Mapping and Sequencing 3. Gene Editing and Genetic Disorders: Ethical and Legal Concerns 4. Political, Regulatory and Ethical Considerations of the CRISPR/Cas Genome Editing Technology 5. CRISPR/Cas and Gene Therapy: An Overview 6. CRISPR and Cancer: From Bench to Clinic 7. The Advances of the CRISPR/Cas9 Technology for Correcting Genetic Disorders: Using Sarcoma as a Model System 8. CRISPR/Cas9 Technology as a Strategy Against Viral Infections 9. CRISPR/Cas9-based Genome and Epigenome Editing in Neuroscience Research 10. Non-viral Alternatives to Delivery of CRISPR-Cas Gene Editing Components 11. CRISPR Medicine: Advance, Progress and Challenges

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• Biologia molecular
• Medicina: temas gerais
• Genética (não médica)
• Genética médica
• Biologia Celular (citologia)

Genome Editing;CRISPR/Cas9;CRISPR Array;Gene editing;Cas9 Mediated Genome Editing;Epigenetics;sgRNA Sequence;Epigenomics;CRISPR Cas System;New medicine;Pam Sequence;Gene therapy;National Academy;Precision medicine;HBB Gene;Genetic disorders;Cas9 Endonuclease;RNA delivary;DNA Methylation;CFTR;Donor DNA;ZFNs;CRISPR Interference;Genome Editing Tools;Germ Line Editing;Guide RNA;Single Guide RNA;Cas Protein;TALENs;DSB;CRISPR RNA;FokI Endonuclease;DNA Sequence Detection;CRISPR