Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

Lin, Chih Li; Singh, Sandeep Kumar; Mishra, Shailendra Kumar

Elsevier Science & Technology

07/2022

410

Mole

Inglês

9780323902359

15 a 20 dias

820

Descrição não disponível.
1. The aging: introduction, theories, principles and future prospective Shabnam Shabir, Mahendra Pratap Singh 2. Brief description of aging in different levels as cellular, tissues, and organs Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Amit Singh 3. Brief about hallmarks of aging Josephine Esposto and Vyshnavy Balendra 4. Overview of various anti-aging strategies Dhiraj Kumar and Faiyaz Ahmad 5. Elimination of damaged cells-dependent anti-aging strategy Rayees Ahmad Naik, Vinodinee Dubey, Roshni Rajpoot, Debabrata Dash, Nidhi Gupta and Raj Kumar Koiri 6. Telomerase reactivation for anti-aging TS Gopenath, Shreya Shreshtha and Kanthesh M. Basalingapa 7. Epigenetic drugs based on anti-aging approach Tarun Minocha, Namrata Dwivedi, Chetan Panda, Anamika Misra, Barsha Baisakhi Nayak, Sanjeev Kumar Yadav, Hareram Birla and Sandeep K. Singh 8. Activation of chaperons and proteolytic system: emerging methods for anti-aging drug development Neha Gogia, Victor Olmos, Fatema Haidery, Kimberly Luttik, Leon Tejwani, Janghoo Lim 9. Dietary restriction and mTOR and IIS inhibition: the potential to anti-aging drug approach Sing-Hua Tsou 10. Anti-Aging Drugs, Candidates, and Food Supplements- The journey so far Yodhaanjali JR, Rithwick Surya, Sumukha KC, Harini G, Gouri Deshpande, Chandan S,Raghu Ram Achar 11. Role of AMPK and Sirtuins as anti-aging proteins Manjula Ramu, Sonali Vishal and Neha Gogia 12. Mitophagy and Mitohormetics: promising anti- aging strategy Chih Li Lin 13. Clearance of senescent cells: potent anti-aging approach Jacques Ferreira and Alex Deamer 14. Stem cell-based therapy as antiaging prospective Sumaira Yusuf, Mahendra P. Singh 15. Anti-inflammatory therapy as a game changer towards anti-aging Dr. Naveen Shivavedi, Anshul Shakya, Bedanta Bhattacharjee and Bhargab Deka 16. Invertebrate model organisms for aging research Arvind Kumar Shukla, Andrew Scott and Edward Giniger
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?AMPK; Age-related disorders; Aging; Aging theories; Aging-associated neurodegenerative diseases; Altered intercellular communication; Animal models; Antiaging; Antiaging approach; Antiaging compounds; Antiaging strategies; Antiaging therapies; Antiinflammatory; Apoptosis; Atrophy; Autophagy; Biological aging; Biomarkers; Calorie restriction; Candidates; Cell death; Cellular; Cellular dysregulation; Cellular reprogramming; Cellular senescence; Dietary restriction (DR); Diseases; Embryonic stem cells; Energy deprivation; Epigenetic drugs; Epigenetic modifications; Exercise; FDA; Fasting; Food supplements; Free radicals; Genomic instability; Hallmarks of aging; Homeostasis; Immunity; Impairment; Inflammaging; Inflammation; Insulin/insulin-like growth factor (IIS); Lifespan extension; Longevity; Mammalian target of Rapamycin (mTOR); Mesenchymal stem cells; Metabolism; Mitochondria; Mitochondrial dysfunction; Mitohormesis; Mitophagy; Molecular; Morphology; Natural compounds; Neurodegeneration; Neurodegenerative disorders; Oxidation; Oxidative stress; Physiology; Plasma transfusion; Protein quality control; Rapamycin; SASP; Senescence; Senolytics; Senomorphic immunomodulators; Senostatic; Sirtuins; Small molecules; Stem cell; Stem cell therapy; Stem cells; Synthetic drugs; Telomerase; Telomerase activators; Telomeres; Therapeutics; Yamanaka factors; Yoga